Radiotherapy‐resistant prostate cancer cells escape immune checkpoint blockade through the senescence‐related ataxia telangiectasia and Rad3‐related protein

Radiotherapy‐resistant prostate cancer cells escape immune checkpoint blockade through the senescence‐related ataxia telangiectasia and Rad3‐related protein

Abstract Background The majority of patients with prostate cancer (PCa) exhibit intrinsic resistance to immune checkpoint blockade (ICB) following radiotherapy (RT). This resistance is generally attributed to the limited antigen presentation of heterogeneous cells within tumors. Here, we aimed to is...

Full description

Saved in:
Bibliographic Details
Main Authors: Chenyi Shao, Yingyi Zhang, Hang Li, Jiajia Chen, Ting Huang, Jiaze Li, Simeng Wen, Sen Wang, Saijun Fan, Yu Zhao
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Cancer Communications
Subjects:
ATR
CD86
immune checkpoint
senescence
Online Access:https://doi.org/10.1002/cac2.12636
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items