Genome-wide reverse genetics framework to identify novel functions of the vertebrate secretome.

Genome-wide reverse genetics framework to identify novel functions of the vertebrate secretome.

<h4>Background</h4>Understanding the functional role(s) of the more than 20,000 proteins of the vertebrate genome is a major next step in the post-genome era. The approximately 4,000 co-translationally translocated (CTT) proteins - representing the vertebrate secretome - are important fo...

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Main Authors: Michael A Pickart, Eric W Klee, Aubrey L Nielsen, Sridhar Sivasubbu, Eric M Mendenhall, Brent R Bill, Eleanor Chen, Craig E Eckfeldt, Michelle Knowlton, Mara E Robu, Jon D Larson, Yun Deng, Lisa A Schimmenti, Lynda B M Ellis, Catherine M Verfaillie, Matthias Hammerschmidt, Steven A Farber, Stephen C Ekker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-12-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0000104&type=printable
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