A robust and lubricating synergic polymer composite for bionic articular cartilage in the load-bearing region
The worldwide ageing of the population and inappropriate exercise lead to damage and wear and tear of articular cartilage in the load-bearing region. This tissue is difficult to regenerate. Therefore, finding a superior biomaterial to replace or substitute the natural cartilage is essential, as it c...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-10-01
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| Series: | Materials & Design |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0264127525010354 |
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| author | Wenjie Ruan Hai Xu Zejian He Yu Tong Qiong Zhang Qing Bi Tianhui Ren Jiao Wang |
| author_facet | Wenjie Ruan Hai Xu Zejian He Yu Tong Qiong Zhang Qing Bi Tianhui Ren Jiao Wang |
| author_sort | Wenjie Ruan |
| collection | DOAJ |
| description | The worldwide ageing of the population and inappropriate exercise lead to damage and wear and tear of articular cartilage in the load-bearing region. This tissue is difficult to regenerate. Therefore, finding a superior biomaterial to replace or substitute the natural cartilage is essential, as it can significantly reduce the risks and pain associated with joint replacement surgery. Herein, we report a novel polymeric material (PU-EP) to achieve synergy of flexibility and rigidity and use it as a medical material to replace natural articular cartilage. This approach skillfully joins the polyurethane and epoxy resin segments, giving the novel polymer network strong mechanical properties and toughness. In addition, the presence of Fe3O4 nanoparticles causes a rolling effect in the composite network PU-EP@NPs under friction, which changes the sliding friction at the friction interface to rolling friction, thus significantly enhancing the lubricity of the network. We believe that this novel polymer network with lubrication function is the most promising material for a class of materials to treat cartilage damage diseases effectively. |
| format | Article |
| id | doaj-art-ad357bdeaa1047db97c34e6e01b00aef |
| institution | Kabale University |
| issn | 0264-1275 |
| language | English |
| publishDate | 2025-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Materials & Design |
| spelling | doaj-art-ad357bdeaa1047db97c34e6e01b00aef2025-08-26T04:14:08ZengElsevierMaterials & Design0264-12752025-10-0125811461510.1016/j.matdes.2025.114615A robust and lubricating synergic polymer composite for bionic articular cartilage in the load-bearing regionWenjie Ruan0Hai Xu1Zejian He2Yu Tong3Qiong Zhang4Qing Bi5Tianhui Ren6Jiao Wang7Center for Rehabilitation Medicine, Department of Orthopedics, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou 310014, China; Department of Sports Medicine, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital), Hangzhou Medical College, Hangzhou, Zhejiang 310000, China; Postgraduate training base Alliance of Wenzhou Medical University, Wenzhou, Zhejiang Province, 325000, ChinaDepartment of Nursing, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou 310000, ChinaStoddart Institute of Molecular Science, Department of Chemistry, ZJU-Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou 310058, China; Corresponding author.Center for Rehabilitation Medicine, Department of Orthopedics, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou 310014, China; Department of Sports Medicine, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital), Hangzhou Medical College, Hangzhou, Zhejiang 310000, ChinaDepartment of Nursing, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou 310000, ChinaCenter for Rehabilitation Medicine, Department of Orthopedics, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou 310014, China; Department of Sports Medicine, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital), Hangzhou Medical College, Hangzhou, Zhejiang 310000, China; Corresponding author at: Center for Rehabilitation Medicine, Department of Orthopedics, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, 310014, PR China.School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, ChinaCenter for Rehabilitation Medicine, Department of Orthopedics, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou 310014, China; Department of Sports Medicine, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital), Hangzhou Medical College, Hangzhou, Zhejiang 310000, China; Corresponding author at: Center for Rehabilitation Medicine, Department of Orthopedics, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, 310014, PR China.The worldwide ageing of the population and inappropriate exercise lead to damage and wear and tear of articular cartilage in the load-bearing region. This tissue is difficult to regenerate. Therefore, finding a superior biomaterial to replace or substitute the natural cartilage is essential, as it can significantly reduce the risks and pain associated with joint replacement surgery. Herein, we report a novel polymeric material (PU-EP) to achieve synergy of flexibility and rigidity and use it as a medical material to replace natural articular cartilage. This approach skillfully joins the polyurethane and epoxy resin segments, giving the novel polymer network strong mechanical properties and toughness. In addition, the presence of Fe3O4 nanoparticles causes a rolling effect in the composite network PU-EP@NPs under friction, which changes the sliding friction at the friction interface to rolling friction, thus significantly enhancing the lubricity of the network. We believe that this novel polymer network with lubrication function is the most promising material for a class of materials to treat cartilage damage diseases effectively.http://www.sciencedirect.com/science/article/pii/S0264127525010354Robust and lubricatingSynergic polymer compositeBionic articular cartilageLoad-bearing region |
| spellingShingle | Wenjie Ruan Hai Xu Zejian He Yu Tong Qiong Zhang Qing Bi Tianhui Ren Jiao Wang A robust and lubricating synergic polymer composite for bionic articular cartilage in the load-bearing region Materials & Design Robust and lubricating Synergic polymer composite Bionic articular cartilage Load-bearing region |
| title | A robust and lubricating synergic polymer composite for bionic articular cartilage in the load-bearing region |
| title_full | A robust and lubricating synergic polymer composite for bionic articular cartilage in the load-bearing region |
| title_fullStr | A robust and lubricating synergic polymer composite for bionic articular cartilage in the load-bearing region |
| title_full_unstemmed | A robust and lubricating synergic polymer composite for bionic articular cartilage in the load-bearing region |
| title_short | A robust and lubricating synergic polymer composite for bionic articular cartilage in the load-bearing region |
| title_sort | robust and lubricating synergic polymer composite for bionic articular cartilage in the load bearing region |
| topic | Robust and lubricating Synergic polymer composite Bionic articular cartilage Load-bearing region |
| url | http://www.sciencedirect.com/science/article/pii/S0264127525010354 |
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