Identification of single stranded RNA fragments recognised by TLR7/8 in Dengue and other mosquito-borne Flaviviral genomes: A bioinformatics approach
Toll-like receptors (TLRs), particularly TLR7 and TLR8, are crucial components of the innate immune system that detect viral single-stranded RNA (ssRNA). However, excessive TLR activation can result in a hyperinflammatory response or “cytokine storm,” contributing to severe disease outcomes. In this...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
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| Series: | The Microbe |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2950194625001748 |
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