A case of vaccine‐associated myocarditis following pneumococcal immunization leading to acute mitral regurgitation
Abstract Vaccine‐associated myocarditis (VAM) is a rare entity but can result in potentially serious sequelae if left untreated. However, the mechanisms of the complications of VAM and its treatment remain unclear. Herein, we report the first case of VAM related to pneumococcal immunization, present...
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| Format: | Article |
| Language: | English |
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Wiley
2022-06-01
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| Series: | ESC Heart Failure |
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| Online Access: | https://doi.org/10.1002/ehf2.13881 |
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| author | Hiroyuki Yamamoto Marie Takahashi Jun Isogai |
| author_facet | Hiroyuki Yamamoto Marie Takahashi Jun Isogai |
| author_sort | Hiroyuki Yamamoto |
| collection | DOAJ |
| description | Abstract Vaccine‐associated myocarditis (VAM) is a rare entity but can result in potentially serious sequelae if left untreated. However, the mechanisms of the complications of VAM and its treatment remain unclear. Herein, we report the first case of VAM related to pneumococcal immunization, presenting as a local and systemic inflammatory reaction, in which the patient developed significant secondary mitral regurgitation, resulting in acute heart failure. Finally, the patient recovered completely following corticosteroid treatment. This case highlights the value of cardiac magnetic resonance and the pitfall of endomyocardial biopsy in establishing the definitive diagnosis of VAM and emphasizes the importance of optimal management in understanding the mechanism and instituting the treatment for secondary mitral regurgitation caused by VAM. |
| format | Article |
| id | doaj-art-ad2183f5c6644fafb873fb448d6721e4 |
| institution | Kabale University |
| issn | 2055-5822 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | ESC Heart Failure |
| spelling | doaj-art-ad2183f5c6644fafb873fb448d6721e42025-02-05T05:22:10ZengWileyESC Heart Failure2055-58222022-06-01932013201910.1002/ehf2.13881A case of vaccine‐associated myocarditis following pneumococcal immunization leading to acute mitral regurgitationHiroyuki Yamamoto0Marie Takahashi1Jun Isogai2Department of Cardiovascular Medicine Narita Tomisato Tokushukai Hospital 1‐1‐1 Hiyoshidai Tomisato Chiba 286‐0201 JapanDepartment of Cardiology Chiba‐Nishi General Hospital Matsudo JapanDepartment of Radiology Asahi General Hospital Asahi JapanAbstract Vaccine‐associated myocarditis (VAM) is a rare entity but can result in potentially serious sequelae if left untreated. However, the mechanisms of the complications of VAM and its treatment remain unclear. Herein, we report the first case of VAM related to pneumococcal immunization, presenting as a local and systemic inflammatory reaction, in which the patient developed significant secondary mitral regurgitation, resulting in acute heart failure. Finally, the patient recovered completely following corticosteroid treatment. This case highlights the value of cardiac magnetic resonance and the pitfall of endomyocardial biopsy in establishing the definitive diagnosis of VAM and emphasizes the importance of optimal management in understanding the mechanism and instituting the treatment for secondary mitral regurgitation caused by VAM.https://doi.org/10.1002/ehf2.13881Vaccine‐associated myocarditisPneumococcal immunizationHeart failureCardiac magnetic resonanceSecondary mitral regurgitation |
| spellingShingle | Hiroyuki Yamamoto Marie Takahashi Jun Isogai A case of vaccine‐associated myocarditis following pneumococcal immunization leading to acute mitral regurgitation ESC Heart Failure Vaccine‐associated myocarditis Pneumococcal immunization Heart failure Cardiac magnetic resonance Secondary mitral regurgitation |
| title | A case of vaccine‐associated myocarditis following pneumococcal immunization leading to acute mitral regurgitation |
| title_full | A case of vaccine‐associated myocarditis following pneumococcal immunization leading to acute mitral regurgitation |
| title_fullStr | A case of vaccine‐associated myocarditis following pneumococcal immunization leading to acute mitral regurgitation |
| title_full_unstemmed | A case of vaccine‐associated myocarditis following pneumococcal immunization leading to acute mitral regurgitation |
| title_short | A case of vaccine‐associated myocarditis following pneumococcal immunization leading to acute mitral regurgitation |
| title_sort | case of vaccine associated myocarditis following pneumococcal immunization leading to acute mitral regurgitation |
| topic | Vaccine‐associated myocarditis Pneumococcal immunization Heart failure Cardiac magnetic resonance Secondary mitral regurgitation |
| url | https://doi.org/10.1002/ehf2.13881 |
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