Electric field stimulation directs target-specific axon regeneration and partial restoration of vision after optic nerve crush injury.

Electric field stimulation directs target-specific axon regeneration and partial restoration of vision after optic nerve crush injury.

Failure of central nervous system (CNS) axons to regenerate after injury results in permanent disability. Several molecular neuro-protective and neuro-regenerative strategies have been proposed as potential treatments but do not provide the directional cues needed to direct target-specific axon rege...

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Main Authors: Timothy Kim, Ege Iseri, Micalla G Peng, Sasha Medvidovic, Timothy Silliman, Pooyan Pahlavan, Gengle Niu, Connie Huang, Anahit Simonyan, Javad Pahnahad, Petcy Yao, Phillip Lam, Vahini Garimella, Mahnaz Shahidi, Michael S Bienkowski, Darrin J Lee, Biju Thomas, Gianluca Lazzi, Kimberly K Gokoffski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0315562
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