Balance between Regulatory T and Th17 Cells in Systemic Lupus Erythematosus: The Old and the New

Balance between Regulatory T and Th17 Cells in Systemic Lupus Erythematosus: The Old and the New

Pathogenic mechanisms underlying the development of systemic lupus erythematosus (SLE) are very complex and not yet entirely clarified. However, the pivotal role of T lymphocytes in the induction and perpetuation of aberrant immune response is well established. Among T cells, IL-17 producing T helpe...

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Main Authors: Alessia Alunno, Elena Bartoloni, Onelia Bistoni, Giuseppe Nocentini, Simona Ronchetti, Sara Caterbi, Valentina Valentini, Carlo Riccardi, Roberto Gerli
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2012/823085
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