Salvage Therapy in Early Relapse of T-Lymphoblastic Leukemia/Lymphoma Using Daratumumab/Nelarabine Combination: Two Consecutive Cases
Treatment of early relapses of T lymphoblastic leukemia/lymphoma is often unsuccessful. We tested an experimental regimen containing daratumumab and nelarabine in two young patients with early relapses of T lymphoblastic lymphoma and T-ALL, respectively. Both patients achieved a deep complete remiss...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2022/9722787 |
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| _version_ | 1832566228566147072 |
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| author | Ingolf Molle Irma Petruskevicius Peter Kamper Francesco d’Amore |
| author_facet | Ingolf Molle Irma Petruskevicius Peter Kamper Francesco d’Amore |
| author_sort | Ingolf Molle |
| collection | DOAJ |
| description | Treatment of early relapses of T lymphoblastic leukemia/lymphoma is often unsuccessful. We tested an experimental regimen containing daratumumab and nelarabine in two young patients with early relapses of T lymphoblastic lymphoma and T-ALL, respectively. Both patients achieved a deep complete remission. Combining daratumumab with chemotherapy may have a role in relapsing T lymphoblastic leukemia/lymphoma. |
| format | Article |
| id | doaj-art-acfcfd62ead64123b003f2790a8716da |
| institution | Kabale University |
| issn | 2090-6579 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-acfcfd62ead64123b003f2790a8716da2025-02-03T01:04:45ZengWileyCase Reports in Hematology2090-65792022-01-01202210.1155/2022/9722787Salvage Therapy in Early Relapse of T-Lymphoblastic Leukemia/Lymphoma Using Daratumumab/Nelarabine Combination: Two Consecutive CasesIngolf Molle0Irma Petruskevicius1Peter Kamper2Francesco d’Amore3Department of HaematologyDepartment of HaematologyDepartment of HaematologyDepartment of HaematologyTreatment of early relapses of T lymphoblastic leukemia/lymphoma is often unsuccessful. We tested an experimental regimen containing daratumumab and nelarabine in two young patients with early relapses of T lymphoblastic lymphoma and T-ALL, respectively. Both patients achieved a deep complete remission. Combining daratumumab with chemotherapy may have a role in relapsing T lymphoblastic leukemia/lymphoma.http://dx.doi.org/10.1155/2022/9722787 |
| spellingShingle | Ingolf Molle Irma Petruskevicius Peter Kamper Francesco d’Amore Salvage Therapy in Early Relapse of T-Lymphoblastic Leukemia/Lymphoma Using Daratumumab/Nelarabine Combination: Two Consecutive Cases Case Reports in Hematology |
| title | Salvage Therapy in Early Relapse of T-Lymphoblastic Leukemia/Lymphoma Using Daratumumab/Nelarabine Combination: Two Consecutive Cases |
| title_full | Salvage Therapy in Early Relapse of T-Lymphoblastic Leukemia/Lymphoma Using Daratumumab/Nelarabine Combination: Two Consecutive Cases |
| title_fullStr | Salvage Therapy in Early Relapse of T-Lymphoblastic Leukemia/Lymphoma Using Daratumumab/Nelarabine Combination: Two Consecutive Cases |
| title_full_unstemmed | Salvage Therapy in Early Relapse of T-Lymphoblastic Leukemia/Lymphoma Using Daratumumab/Nelarabine Combination: Two Consecutive Cases |
| title_short | Salvage Therapy in Early Relapse of T-Lymphoblastic Leukemia/Lymphoma Using Daratumumab/Nelarabine Combination: Two Consecutive Cases |
| title_sort | salvage therapy in early relapse of t lymphoblastic leukemia lymphoma using daratumumab nelarabine combination two consecutive cases |
| url | http://dx.doi.org/10.1155/2022/9722787 |
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