Investigating Raman peak enhancement in carboxyl-rich molecules: insights from Au@Ag core-shell nanoparticles in colloids
Surface-enhanced Raman scattering (SERS) is a promising analytical technique with applications in environmental monitoring, healthcare, and the biopharmaceutical industry. While SERS has been successfully applied to molecules such as 4-mercaptobenzoic acid and other thiol- and amine-containing compo...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Chemistry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fchem.2025.1522043/full |
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| author | Junhao Chen Zhengjia Chen Tong Liang Zhennan Zhang Dahang Cheng Shurui Liu Haiyang Liu Cuicui Liu Xiaohui Song |
| author_facet | Junhao Chen Zhengjia Chen Tong Liang Zhennan Zhang Dahang Cheng Shurui Liu Haiyang Liu Cuicui Liu Xiaohui Song |
| author_sort | Junhao Chen |
| collection | DOAJ |
| description | Surface-enhanced Raman scattering (SERS) is a promising analytical technique with applications in environmental monitoring, healthcare, and the biopharmaceutical industry. While SERS has been successfully applied to molecules such as 4-mercaptobenzoic acid and other thiol- and amine-containing compounds, there is limited research on its detection capabilities for molecules rich in carboxyl groups or unsaturated bonds, such as citric acid. This study investigates the SERS enhancement of Au@Ag core-shell nanoparticles in response to citric acid and other molecules with carboxyl and unsaturated bonds. We compare the SERS behavior of nanoparticles in freshly prepared and aged sodium citrate solutions to identify differences in Raman peak enhancement. Our findings show that the Au@Ag core-shell nanoparticles exhibit significant SERS enhancement when exposed to citric acid and other related compounds. The enhancement varies based on the age of the sodium citrate solution, which influences the structural properties of the nanoparticles. This work opens avenues for further research and applications in biological monitoring, environmental testing, and the pharmaceutical industry. |
| format | Article |
| id | doaj-art-acf75581d0374a84b9f657b878847155 |
| institution | Kabale University |
| issn | 2296-2646 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Chemistry |
| spelling | doaj-art-acf75581d0374a84b9f657b8788471552025-01-27T06:41:02ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462025-01-011310.3389/fchem.2025.15220431522043Investigating Raman peak enhancement in carboxyl-rich molecules: insights from Au@Ag core-shell nanoparticles in colloidsJunhao Chen0Zhengjia Chen1Tong Liang2Zhennan Zhang3Dahang Cheng4Shurui Liu5Haiyang Liu6Cuicui Liu7Xiaohui Song8School of Materials Science and Engineering, Hefei University of Technology, Hefei, Anhui, ChinaGeneral Education and International School, Chongqing Polytechnic University of Electronic Technology, Chongqing, ChinaSchool of Materials Science and Engineering, Hefei University of Technology, Hefei, Anhui, ChinaSchool of Materials Science and Engineering, Hefei University of Technology, Hefei, Anhui, ChinaSchool of Materials Science and Engineering, Hefei University of Technology, Hefei, Anhui, ChinaSchool of Materials Science and Engineering, Hefei University of Technology, Hefei, Anhui, ChinaSchool of Materials Science and Engineering, Hefei University of Technology, Hefei, Anhui, ChinaDepartment of Chemistry and Biochemistry, Nanyang Technological University, Singapore, SingaporeSchool of Materials Science and Engineering, Hefei University of Technology, Hefei, Anhui, ChinaSurface-enhanced Raman scattering (SERS) is a promising analytical technique with applications in environmental monitoring, healthcare, and the biopharmaceutical industry. While SERS has been successfully applied to molecules such as 4-mercaptobenzoic acid and other thiol- and amine-containing compounds, there is limited research on its detection capabilities for molecules rich in carboxyl groups or unsaturated bonds, such as citric acid. This study investigates the SERS enhancement of Au@Ag core-shell nanoparticles in response to citric acid and other molecules with carboxyl and unsaturated bonds. We compare the SERS behavior of nanoparticles in freshly prepared and aged sodium citrate solutions to identify differences in Raman peak enhancement. Our findings show that the Au@Ag core-shell nanoparticles exhibit significant SERS enhancement when exposed to citric acid and other related compounds. The enhancement varies based on the age of the sodium citrate solution, which influences the structural properties of the nanoparticles. This work opens avenues for further research and applications in biological monitoring, environmental testing, and the pharmaceutical industry.https://www.frontiersin.org/articles/10.3389/fchem.2025.1522043/fullsurface-enhanced Raman scatteringAu@Ag core-shell nanoparticlescitric acidcarboxyl-rich moleculecolloidal |
| spellingShingle | Junhao Chen Zhengjia Chen Tong Liang Zhennan Zhang Dahang Cheng Shurui Liu Haiyang Liu Cuicui Liu Xiaohui Song Investigating Raman peak enhancement in carboxyl-rich molecules: insights from Au@Ag core-shell nanoparticles in colloids Frontiers in Chemistry surface-enhanced Raman scattering Au@Ag core-shell nanoparticles citric acid carboxyl-rich molecule colloidal |
| title | Investigating Raman peak enhancement in carboxyl-rich molecules: insights from Au@Ag core-shell nanoparticles in colloids |
| title_full | Investigating Raman peak enhancement in carboxyl-rich molecules: insights from Au@Ag core-shell nanoparticles in colloids |
| title_fullStr | Investigating Raman peak enhancement in carboxyl-rich molecules: insights from Au@Ag core-shell nanoparticles in colloids |
| title_full_unstemmed | Investigating Raman peak enhancement in carboxyl-rich molecules: insights from Au@Ag core-shell nanoparticles in colloids |
| title_short | Investigating Raman peak enhancement in carboxyl-rich molecules: insights from Au@Ag core-shell nanoparticles in colloids |
| title_sort | investigating raman peak enhancement in carboxyl rich molecules insights from au ag core shell nanoparticles in colloids |
| topic | surface-enhanced Raman scattering Au@Ag core-shell nanoparticles citric acid carboxyl-rich molecule colloidal |
| url | https://www.frontiersin.org/articles/10.3389/fchem.2025.1522043/full |
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