Synthesis and Antimicrobial Activity of Newer Quinazolinones
2–alkyl–6–bromo–3,1–benzoxazine–4–one (2) is synthesized by treating p–Bromoanthranilic acid and Acetylechoride or Benzoylchloride. Reaction of 2–alkyl–6–bromo–3,1–benzoxazine–4–one (2). with hydrazinehydrate furnish the corresponding 3–Amino–2–methyl–6–bromoquinazoline–4(3H)–one (3) which on react...
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| Format: | Article |
| Language: | English |
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Wiley
2006-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2006/586512 |
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| author | J. A. Patel B. D. Mistry K. R. Desai |
| author_facet | J. A. Patel B. D. Mistry K. R. Desai |
| author_sort | J. A. Patel |
| collection | DOAJ |
| description | 2–alkyl–6–bromo–3,1–benzoxazine–4–one (2) is synthesized by treating p–Bromoanthranilic acid and Acetylechoride or Benzoylchloride. Reaction of 2–alkyl–6–bromo–3,1–benzoxazine–4–one (2). with hydrazinehydrate furnish the corresponding 3–Amino–2–methyl–6–bromoquinazoline–4(3H)–one (3) which on reaction with benzaldehyde afford N,N – arylidene derivative (4). Reaction of 4 with various diazonium salts yields 6–bromo–2–alkyl/aryl–3{[phenyl(phenyldiazenyl)methylene]amino}quinazolin–4(3H)–one . |
| format | Article |
| id | doaj-art-acec0881641e43a4b63b4205574930d8 |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2006-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-acec0881641e43a4b63b4205574930d82025-02-03T01:01:50ZengWileyE-Journal of Chemistry0973-49452090-98102006-01-01329710210.1155/2006/586512Synthesis and Antimicrobial Activity of Newer QuinazolinonesJ. A. Patel0B. D. Mistry1K. R. Desai2Department of Chemistry, B. K. M. Science College, Valsad–396001, IndiaDepartment of Chemistry, B. K. M. Science College, Valsad–396001, IndiaDepartment of Chemistry, Veer Narmad South Gujarat University, Surat–395007, India2–alkyl–6–bromo–3,1–benzoxazine–4–one (2) is synthesized by treating p–Bromoanthranilic acid and Acetylechoride or Benzoylchloride. Reaction of 2–alkyl–6–bromo–3,1–benzoxazine–4–one (2). with hydrazinehydrate furnish the corresponding 3–Amino–2–methyl–6–bromoquinazoline–4(3H)–one (3) which on reaction with benzaldehyde afford N,N – arylidene derivative (4). Reaction of 4 with various diazonium salts yields 6–bromo–2–alkyl/aryl–3{[phenyl(phenyldiazenyl)methylene]amino}quinazolin–4(3H)–one .http://dx.doi.org/10.1155/2006/586512 |
| spellingShingle | J. A. Patel B. D. Mistry K. R. Desai Synthesis and Antimicrobial Activity of Newer Quinazolinones E-Journal of Chemistry |
| title | Synthesis and Antimicrobial Activity of Newer Quinazolinones |
| title_full | Synthesis and Antimicrobial Activity of Newer Quinazolinones |
| title_fullStr | Synthesis and Antimicrobial Activity of Newer Quinazolinones |
| title_full_unstemmed | Synthesis and Antimicrobial Activity of Newer Quinazolinones |
| title_short | Synthesis and Antimicrobial Activity of Newer Quinazolinones |
| title_sort | synthesis and antimicrobial activity of newer quinazolinones |
| url | http://dx.doi.org/10.1155/2006/586512 |
| work_keys_str_mv | AT japatel synthesisandantimicrobialactivityofnewerquinazolinones AT bdmistry synthesisandantimicrobialactivityofnewerquinazolinones AT krdesai synthesisandantimicrobialactivityofnewerquinazolinones |