Synthesis and Antimicrobial Activity of Newer Quinazolinones
2–alkyl–6–bromo–3,1–benzoxazine–4–one (2) is synthesized by treating p–Bromoanthranilic acid and Acetylechoride or Benzoylchloride. Reaction of 2–alkyl–6–bromo–3,1–benzoxazine–4–one (2). with hydrazinehydrate furnish the corresponding 3–Amino–2–methyl–6–bromoquinazoline–4(3H)–one (3) which on react...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2006-01-01
|
| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2006/586512 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | 2–alkyl–6–bromo–3,1–benzoxazine–4–one (2) is synthesized by treating p–Bromoanthranilic acid and Acetylechoride or Benzoylchloride. Reaction of 2–alkyl–6–bromo–3,1–benzoxazine–4–one (2). with hydrazinehydrate furnish the corresponding 3–Amino–2–methyl–6–bromoquinazoline–4(3H)–one (3) which on reaction with benzaldehyde afford N,N – arylidene derivative (4). Reaction of 4 with various diazonium salts yields 6–bromo–2–alkyl/aryl–3{[phenyl(phenyldiazenyl)methylene]amino}quinazolin–4(3H)–one . |
|---|---|
| ISSN: | 0973-4945 2090-9810 |