Near-Infrared Photoimmunotherapy in Brain Tumors—An Unexplored Frontier

Near-Infrared Photoimmunotherapy in Brain Tumors—An Unexplored Frontier

Near-infrared photoimmunotherapy (NIR-PIT) is a promising cancer treatment that uses near-infrared light to activate a conjugate of a monoclonal antibody (mAb) and a photoactivatable silica phthalocyanine dye (IRDye700DX: IR700). Unlike conventional photodynamic therapy (PDT), NIR-PIT selectively de...

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Bibliographic Details
Main Authors: Haruka Yamaguchi, Masayasu Okada, Takuya Otani, Jotaro On, Satoshi Shibuma, Toru Takino, Jun Watanabe, Yoshihiro Tsukamoto, Ryosuke Ogura, Makoto Oishi, Takamasa Suzuki, Akihiro Ishikawa, Hideyuki Sakata, Manabu Natsumeda
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Pharmaceuticals
Subjects:
near-infrared photoimmunotherapy
IR700
photodynamic therapy
central nervous system
brain tumors
glioma
Online Access:https://www.mdpi.com/1424-8247/18/5/751
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