Determining the Diagnostic Value of DWIBS in the Diagnosis of Breast Lesions Compared to Dynamic Contrast-Enhanced MRI: A Retrospective Observational Study
Background: Diffusion-weighted imaging with background body signal suppression (DWIBS) is a new imaging tool for the diagnosis of breast lesions. This study aims to compare DWIBS with contrast-enhanced magnetic resonance imaging (CE-MRI) sequences. Materials and Methods: Eighty consecutive patients...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | Advanced Biomedical Research |
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| Online Access: | https://journals.lww.com/10.4103/abr.abr_283_24 |
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| author | Maryam Farghadani Safura Mozafari Maryam Riahinejad Mashid Haghighi Reza Eshraghi Samani Amir Mohammad Taravati Koushan Rostami Seyedeh Ghazal Shahrokh Arezoo Sadeghian |
| author_facet | Maryam Farghadani Safura Mozafari Maryam Riahinejad Mashid Haghighi Reza Eshraghi Samani Amir Mohammad Taravati Koushan Rostami Seyedeh Ghazal Shahrokh Arezoo Sadeghian |
| author_sort | Maryam Farghadani |
| collection | DOAJ |
| description | Background:
Diffusion-weighted imaging with background body signal suppression (DWIBS) is a new imaging tool for the diagnosis of breast lesions. This study aims to compare DWIBS with contrast-enhanced magnetic resonance imaging (CE-MRI) sequences.
Materials and Methods:
Eighty consecutive patients underwent both CE-MRI and DWIBS images. DWIBS was assessed qualitatively and quantitatively using the apparent diffusion coefficient mapping. A threshold of 1.44 × 10-3 mm2/s was considered as a cutoff value between malignant and benign lesions. CE-MRI images were evaluated based on a combination of kinetic and morphological information and reported using Breast Imaging Reporting and Data System lexicon. Statistical analysis was performed for both sequences based on pathologic findings as a gold standard.
Results:
Fifty-five out of 80 lesions (69%) were benign, and 25 malignant lesions (31%) have been reported. The sensitivity, specificity, positive predictive value, and negative predictive value for CE-MRI were 100, 38, 42, and 100%, respectively, and those for DWIBS were 77, 70, 53, and 87%, respectively. By comparing DWIBS and CE-MRI data, no statistically significant difference was reported.
Conclusion:
DWIBS can be used as an effective alternative for breast CE-MRI in cases of contradictions of IV contrast injection. |
| format | Article |
| id | doaj-art-acc733447f144754abd38b8837afe37d |
| institution | Kabale University |
| issn | 2277-9175 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Advanced Biomedical Research |
| spelling | doaj-art-acc733447f144754abd38b8837afe37d2025-02-06T09:41:42ZengWolters Kluwer Medknow PublicationsAdvanced Biomedical Research2277-91752025-01-011416610.4103/abr.abr_283_24Determining the Diagnostic Value of DWIBS in the Diagnosis of Breast Lesions Compared to Dynamic Contrast-Enhanced MRI: A Retrospective Observational StudyMaryam FarghadaniSafura MozafariMaryam RiahinejadMashid HaghighiReza Eshraghi SamaniAmir Mohammad TaravatiKoushan RostamiSeyedeh Ghazal ShahrokhArezoo SadeghianBackground: Diffusion-weighted imaging with background body signal suppression (DWIBS) is a new imaging tool for the diagnosis of breast lesions. This study aims to compare DWIBS with contrast-enhanced magnetic resonance imaging (CE-MRI) sequences. Materials and Methods: Eighty consecutive patients underwent both CE-MRI and DWIBS images. DWIBS was assessed qualitatively and quantitatively using the apparent diffusion coefficient mapping. A threshold of 1.44 × 10-3 mm2/s was considered as a cutoff value between malignant and benign lesions. CE-MRI images were evaluated based on a combination of kinetic and morphological information and reported using Breast Imaging Reporting and Data System lexicon. Statistical analysis was performed for both sequences based on pathologic findings as a gold standard. Results: Fifty-five out of 80 lesions (69%) were benign, and 25 malignant lesions (31%) have been reported. The sensitivity, specificity, positive predictive value, and negative predictive value for CE-MRI were 100, 38, 42, and 100%, respectively, and those for DWIBS were 77, 70, 53, and 87%, respectively. By comparing DWIBS and CE-MRI data, no statistically significant difference was reported. Conclusion: DWIBS can be used as an effective alternative for breast CE-MRI in cases of contradictions of IV contrast injection.https://journals.lww.com/10.4103/abr.abr_283_24breast cancerdiffusion magnetic resonance imagingmagnetic resonance imaging |
| spellingShingle | Maryam Farghadani Safura Mozafari Maryam Riahinejad Mashid Haghighi Reza Eshraghi Samani Amir Mohammad Taravati Koushan Rostami Seyedeh Ghazal Shahrokh Arezoo Sadeghian Determining the Diagnostic Value of DWIBS in the Diagnosis of Breast Lesions Compared to Dynamic Contrast-Enhanced MRI: A Retrospective Observational Study Advanced Biomedical Research breast cancer diffusion magnetic resonance imaging magnetic resonance imaging |
| title | Determining the Diagnostic Value of DWIBS in the Diagnosis of Breast Lesions Compared to Dynamic Contrast-Enhanced MRI: A Retrospective Observational Study |
| title_full | Determining the Diagnostic Value of DWIBS in the Diagnosis of Breast Lesions Compared to Dynamic Contrast-Enhanced MRI: A Retrospective Observational Study |
| title_fullStr | Determining the Diagnostic Value of DWIBS in the Diagnosis of Breast Lesions Compared to Dynamic Contrast-Enhanced MRI: A Retrospective Observational Study |
| title_full_unstemmed | Determining the Diagnostic Value of DWIBS in the Diagnosis of Breast Lesions Compared to Dynamic Contrast-Enhanced MRI: A Retrospective Observational Study |
| title_short | Determining the Diagnostic Value of DWIBS in the Diagnosis of Breast Lesions Compared to Dynamic Contrast-Enhanced MRI: A Retrospective Observational Study |
| title_sort | determining the diagnostic value of dwibs in the diagnosis of breast lesions compared to dynamic contrast enhanced mri a retrospective observational study |
| topic | breast cancer diffusion magnetic resonance imaging magnetic resonance imaging |
| url | https://journals.lww.com/10.4103/abr.abr_283_24 |
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