Diagnosis of Distal Cholangiocarcinoma after the Removal of Choledocholithiasis
Background and Aim. Distal cholangiocarcinoma associated with choledocholithiasis has not been reported, and the causal relationship remains to be established. We evaluated diagnosis of distal cholangiocarcinoma diagnosed after the removal of choledocholithiasis. Patients and Methods. We assigned 9...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2012/396869 |
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| author | Yasuhiro Ito Takeshi Kenmochi Tomohisa Egawa Shinobu Hayashi Atsushi Nagashima Yuko Kitagawa |
| author_facet | Yasuhiro Ito Takeshi Kenmochi Tomohisa Egawa Shinobu Hayashi Atsushi Nagashima Yuko Kitagawa |
| author_sort | Yasuhiro Ito |
| collection | DOAJ |
| description | Background and Aim. Distal cholangiocarcinoma associated with choledocholithiasis has not been reported, and the causal relationship remains to be established. We evaluated diagnosis of distal cholangiocarcinoma diagnosed after the removal of choledocholithiasis. Patients and Methods. We assigned 9 cases of cholangiocarcinoma with choledocholithiasis to Group A. As a control group, 37 patients with cholangiocarcinoma without choledocholithiasis were assigned to Group B. Results. Abdominal pain at admission is the only significant difference between Group A and Group B (P=0.001). All patients in Group A had gall bladder stones, compared with 7 patients (19%) in Group B (P<0.01). Of the 9 patients in Group A, endoscopic retrade cholangiopancreatography (ERCP) detected normality in 2 patients (22%) and abnormalities in 7 patients (78%). Of the 32 patients in Group B, ERCP detected normality in 4 patients (13%) and abnormalities in 28 patients (88%) (P=0.597). Intraductal ultrasonography (IDUS) detected a tumor in 8 patients in Group A, while in Group B, IDUS detected normality in 1 patient (3%) and tumors in 29 patients (97%) (P=1.000). Conclusions. IDUS after stone removal may potentially help in the detection of unexpected tumors. Therefore, we believe that IDUS after stone removal will lead to improve outcome and prognosis. |
| format | Article |
| id | doaj-art-acc24152744d453984ac0a15bf17c912 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-acc24152744d453984ac0a15bf17c9122025-02-03T01:29:10ZengWileyGastroenterology Research and Practice1687-61211687-630X2012-01-01201210.1155/2012/396869396869Diagnosis of Distal Cholangiocarcinoma after the Removal of CholedocholithiasisYasuhiro Ito0Takeshi Kenmochi1Tomohisa Egawa2Shinobu Hayashi3Atsushi Nagashima4Yuko Kitagawa5Department of Surgery, Saiseikai Yokohamashi Tobu Hospital, 3-6-1 Shimosueyoshi, Tsurumi-ku, Yokohama-shi, Kanagawa 230-8765, JapanDepartment of Surgery, Saiseikai Yokohamashi Tobu Hospital, 3-6-1 Shimosueyoshi, Tsurumi-ku, Yokohama-shi, Kanagawa 230-8765, JapanDepartment of Surgery, Saiseikai Yokohamashi Tobu Hospital, 3-6-1 Shimosueyoshi, Tsurumi-ku, Yokohama-shi, Kanagawa 230-8765, JapanDepartment of Surgery, Saiseikai Yokohamashi Tobu Hospital, 3-6-1 Shimosueyoshi, Tsurumi-ku, Yokohama-shi, Kanagawa 230-8765, JapanDepartment of Surgery, Saiseikai Yokohamashi Tobu Hospital, 3-6-1 Shimosueyoshi, Tsurumi-ku, Yokohama-shi, Kanagawa 230-8765, JapanDepartment of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, JapanBackground and Aim. Distal cholangiocarcinoma associated with choledocholithiasis has not been reported, and the causal relationship remains to be established. We evaluated diagnosis of distal cholangiocarcinoma diagnosed after the removal of choledocholithiasis. Patients and Methods. We assigned 9 cases of cholangiocarcinoma with choledocholithiasis to Group A. As a control group, 37 patients with cholangiocarcinoma without choledocholithiasis were assigned to Group B. Results. Abdominal pain at admission is the only significant difference between Group A and Group B (P=0.001). All patients in Group A had gall bladder stones, compared with 7 patients (19%) in Group B (P<0.01). Of the 9 patients in Group A, endoscopic retrade cholangiopancreatography (ERCP) detected normality in 2 patients (22%) and abnormalities in 7 patients (78%). Of the 32 patients in Group B, ERCP detected normality in 4 patients (13%) and abnormalities in 28 patients (88%) (P=0.597). Intraductal ultrasonography (IDUS) detected a tumor in 8 patients in Group A, while in Group B, IDUS detected normality in 1 patient (3%) and tumors in 29 patients (97%) (P=1.000). Conclusions. IDUS after stone removal may potentially help in the detection of unexpected tumors. Therefore, we believe that IDUS after stone removal will lead to improve outcome and prognosis.http://dx.doi.org/10.1155/2012/396869 |
| spellingShingle | Yasuhiro Ito Takeshi Kenmochi Tomohisa Egawa Shinobu Hayashi Atsushi Nagashima Yuko Kitagawa Diagnosis of Distal Cholangiocarcinoma after the Removal of Choledocholithiasis Gastroenterology Research and Practice |
| title | Diagnosis of Distal Cholangiocarcinoma after the Removal of Choledocholithiasis |
| title_full | Diagnosis of Distal Cholangiocarcinoma after the Removal of Choledocholithiasis |
| title_fullStr | Diagnosis of Distal Cholangiocarcinoma after the Removal of Choledocholithiasis |
| title_full_unstemmed | Diagnosis of Distal Cholangiocarcinoma after the Removal of Choledocholithiasis |
| title_short | Diagnosis of Distal Cholangiocarcinoma after the Removal of Choledocholithiasis |
| title_sort | diagnosis of distal cholangiocarcinoma after the removal of choledocholithiasis |
| url | http://dx.doi.org/10.1155/2012/396869 |
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