InCl3-Catalyzed [2+3] Cycloaddition Reaction: A Rapid Synthesis of 5-Substituted 1H-tetrazole under Microwave Irradiation
A series of 5-substituted 1H-tetrazole were efficiently prepared by InCl3 catalyzed (10 mol %) from structurally divert organic nitriles with sodium azide under the influence of microwave irradiation. The present protocol was successfully applied to the aliphatic, aryl, benzylic and heterocyclic nit...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2012/615891 |
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| author | Vijay S. Patil Kamlakar P. Nandre Amulrao U. Borse Sidhanath V. Bhosale |
| author_facet | Vijay S. Patil Kamlakar P. Nandre Amulrao U. Borse Sidhanath V. Bhosale |
| author_sort | Vijay S. Patil |
| collection | DOAJ |
| description | A series of 5-substituted 1H-tetrazole were efficiently prepared by InCl3 catalyzed (10 mol %) from structurally divert organic nitriles with sodium azide under the influence of microwave irradiation. The present protocol was successfully applied to the aliphatic, aryl, benzylic and heterocyclic nitriles and corresponding 5-substituted 1H-tetrazole were obtained in good to excellent yield (70-96%). This method gives remarkable advantages such as short reaction time, simple work-up procedure and economical beneficial. |
| format | Article |
| id | doaj-art-aca425ada51c4f01a5417e1671e06b36 |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-aca425ada51c4f01a5417e1671e06b362025-02-03T01:02:05ZengWileyE-Journal of Chemistry0973-49452090-98102012-01-01931145115210.1155/2012/615891InCl3-Catalyzed [2+3] Cycloaddition Reaction: A Rapid Synthesis of 5-Substituted 1H-tetrazole under Microwave IrradiationVijay S. Patil0Kamlakar P. Nandre1Amulrao U. Borse2Sidhanath V. Bhosale3Department of Organic Chemistry, North Maharashtra University, Umavinagar, IndiaDepartment of Organic Chemistry, North Maharashtra University, Umavinagar, IndiaSchool of Chemical Sciences, North Maharashtra University, Jalgaon, IndiaDepartment of Organic Chemistry, North Maharashtra University, Umavinagar, IndiaA series of 5-substituted 1H-tetrazole were efficiently prepared by InCl3 catalyzed (10 mol %) from structurally divert organic nitriles with sodium azide under the influence of microwave irradiation. The present protocol was successfully applied to the aliphatic, aryl, benzylic and heterocyclic nitriles and corresponding 5-substituted 1H-tetrazole were obtained in good to excellent yield (70-96%). This method gives remarkable advantages such as short reaction time, simple work-up procedure and economical beneficial.http://dx.doi.org/10.1155/2012/615891 |
| spellingShingle | Vijay S. Patil Kamlakar P. Nandre Amulrao U. Borse Sidhanath V. Bhosale InCl3-Catalyzed [2+3] Cycloaddition Reaction: A Rapid Synthesis of 5-Substituted 1H-tetrazole under Microwave Irradiation E-Journal of Chemistry |
| title | InCl3-Catalyzed [2+3] Cycloaddition Reaction: A Rapid Synthesis of 5-Substituted 1H-tetrazole under Microwave Irradiation |
| title_full | InCl3-Catalyzed [2+3] Cycloaddition Reaction: A Rapid Synthesis of 5-Substituted 1H-tetrazole under Microwave Irradiation |
| title_fullStr | InCl3-Catalyzed [2+3] Cycloaddition Reaction: A Rapid Synthesis of 5-Substituted 1H-tetrazole under Microwave Irradiation |
| title_full_unstemmed | InCl3-Catalyzed [2+3] Cycloaddition Reaction: A Rapid Synthesis of 5-Substituted 1H-tetrazole under Microwave Irradiation |
| title_short | InCl3-Catalyzed [2+3] Cycloaddition Reaction: A Rapid Synthesis of 5-Substituted 1H-tetrazole under Microwave Irradiation |
| title_sort | incl3 catalyzed 2 3 cycloaddition reaction a rapid synthesis of 5 substituted 1h tetrazole under microwave irradiation |
| url | http://dx.doi.org/10.1155/2012/615891 |
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