Analysis of genetic polymorphisms and drug resistance mutations in the NS5 region of HCV genome (Flasuviricetes: Amarillovirales: Flaviviridae: <i>Hepacivirus C</i>) in samples obtained in 2022–2023 from HIV-infected treatment-naive residents of Altai Krai

Analysis of genetic polymorphisms and drug resistance mutations in the NS5 region of HCV genome (Flasuviricetes: Amarillovirales: Flaviviridae: <i>Hepacivirus C</i>) in samples obtained in 2022–2023 from HIV-infected treatment-naive residents of Altai Krai

Introduction. Altai Krai is a region with an unfavorable situation of HIV-1 and HCV infection, as well as HIV-1 and HCV coinfection. Due to this, it is necessary to study the HCV genetic variants and their drug resistance (DR) to direct-acting antivirals (DAAs) in patients with HIV-1 and HCV coinfec...

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Main Authors: Ilya A. Lapovok, Arina V. Syrkina, Alina A. Kirichenko, Anastasia V. Shlykova, Natalya V. Lukyanenko, Tatyana V. Safyanova, Arina E. Safronova, Valery V. Shevchenko, Dmitry E. Kireev
Format: Article
Language:English
Published: Central Research Institute for Epidemiology 2025-07-01
Series:Вопросы вирусологии
Subjects:
hiv-1
hcv
coinfection
genotyping
subtype
ns5a
ns5b
drug resistance
Online Access:https://virusjour.crie.ru/jour/article/viewFile/16722/981
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