Generation of Anti‐Mastitis Gene‐Edited Dairy Goats with Enhancing Lysozyme Expression by Inflammatory Regulatory Sequence using ISDra2‐TnpB System

Generation of Anti‐Mastitis Gene‐Edited Dairy Goats with Enhancing Lysozyme Expression by Inflammatory Regulatory Sequence using ISDra2‐TnpB System

Abstract Gene‐editing technology has become a transformative tool for the precise manipulation of biological genomes and holds great significance in the field of animal disease‐resistant breeding. Mastitis, a prevalent disease in animal husbandry, imposes a substantial economic burden on the global...

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Main Authors: Rui Feng, Jianglin Zhao, Qian Zhang, Zhenliang Zhu, Junyu Zhang, Chengyuan Liu, Xiaoman Zheng, Fan Wang, Jie Su, Xianghai Ma, Xiaoyu Mi, Lin Guo, Xiaoxue Yan, Yayi Liu, Huijia Li, Xu Chen, Yi Deng, Guoyan Wang, Yong Zhang, Xu Liu, Jun Liu
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:Advanced Science
Subjects:
gene‐editing breeding strategy
goats
ISDra2‐TnpB system
mastitis
Online Access:https://doi.org/10.1002/advs.202404408
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https://doi.org/10.1002/advs.202404408

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