Non-Helicobacter pylori Gastric Intestinal Metaplasia in Children: A Series of Cases and Review of the Literature
In the pediatric population, Gastric Intestinal Metaplasia (GIM) is a finding with unknown frequency and, more importantly, unknown clinical implications. The relationship between Helicobacter pylori (HP) infection and GIM is well documented, as well as an association between duodenogastric reflux a...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2018/5930415 |
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| author | Sandra Mabel Camacho-Gomez Anas Bernieh Ali G. Saad Neelesh Ajit Tipnis |
| author_facet | Sandra Mabel Camacho-Gomez Anas Bernieh Ali G. Saad Neelesh Ajit Tipnis |
| author_sort | Sandra Mabel Camacho-Gomez |
| collection | DOAJ |
| description | In the pediatric population, Gastric Intestinal Metaplasia (GIM) is a finding with unknown frequency and, more importantly, unknown clinical implications. The relationship between Helicobacter pylori (HP) infection and GIM is well documented, as well as an association between duodenogastric reflux and GIM. We present two cases of pediatric patients with GIM along with a review of the literature. The diagnosis of GIM may have adverse clinical implications and should be made with caution in a child. The association of GIM and adenoma/dysplasia and carcinoma is rarely seen in children, primarily because the time required for these to develop takes the individual into adulthood. Treatment, long-term consequences, and surveillance protocols are not well established in the pediatric population. Studies to evaluate the long-term natural history, treatment, and surveillance protocols in children with GIM are needed. |
| format | Article |
| id | doaj-art-ac5057a683e746f2a8cb8b4f20538f9a |
| institution | Kabale University |
| issn | 2090-6528 2090-6536 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-ac5057a683e746f2a8cb8b4f20538f9a2025-02-03T06:13:50ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362018-01-01201810.1155/2018/59304155930415Non-Helicobacter pylori Gastric Intestinal Metaplasia in Children: A Series of Cases and Review of the LiteratureSandra Mabel Camacho-Gomez0Anas Bernieh1Ali G. Saad2Neelesh Ajit Tipnis3Department of Pediatrics, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USADepartment of Pathology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USADepartment of Pathology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USADepartment of Pediatrics, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USAIn the pediatric population, Gastric Intestinal Metaplasia (GIM) is a finding with unknown frequency and, more importantly, unknown clinical implications. The relationship between Helicobacter pylori (HP) infection and GIM is well documented, as well as an association between duodenogastric reflux and GIM. We present two cases of pediatric patients with GIM along with a review of the literature. The diagnosis of GIM may have adverse clinical implications and should be made with caution in a child. The association of GIM and adenoma/dysplasia and carcinoma is rarely seen in children, primarily because the time required for these to develop takes the individual into adulthood. Treatment, long-term consequences, and surveillance protocols are not well established in the pediatric population. Studies to evaluate the long-term natural history, treatment, and surveillance protocols in children with GIM are needed.http://dx.doi.org/10.1155/2018/5930415 |
| spellingShingle | Sandra Mabel Camacho-Gomez Anas Bernieh Ali G. Saad Neelesh Ajit Tipnis Non-Helicobacter pylori Gastric Intestinal Metaplasia in Children: A Series of Cases and Review of the Literature Case Reports in Gastrointestinal Medicine |
| title | Non-Helicobacter pylori Gastric Intestinal Metaplasia in Children: A Series of Cases and Review of the Literature |
| title_full | Non-Helicobacter pylori Gastric Intestinal Metaplasia in Children: A Series of Cases and Review of the Literature |
| title_fullStr | Non-Helicobacter pylori Gastric Intestinal Metaplasia in Children: A Series of Cases and Review of the Literature |
| title_full_unstemmed | Non-Helicobacter pylori Gastric Intestinal Metaplasia in Children: A Series of Cases and Review of the Literature |
| title_short | Non-Helicobacter pylori Gastric Intestinal Metaplasia in Children: A Series of Cases and Review of the Literature |
| title_sort | non helicobacter pylori gastric intestinal metaplasia in children a series of cases and review of the literature |
| url | http://dx.doi.org/10.1155/2018/5930415 |
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