Drug and cell type-specific regulation of genes with different classes of estrogen receptor beta-selective agonists.

Drug and cell type-specific regulation of genes with different classes of estrogen receptor beta-selective agonists.

Estrogens produce biological effects by interacting with two estrogen receptors, ERalpha and ERbeta. Drugs that selectively target ERalpha or ERbeta might be safer for conditions that have been traditionally treated with non-selective estrogens. Several synthetic and natural ERbeta-selective compoun...

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Main Authors: Sreenivasan Paruthiyil, Aleksandra Cvoro, Xiaoyue Zhao, Zhijin Wu, Yunxia Sui, Richard E Staub, Scott Baggett, Candice B Herber, Chandi Griffin, Mary Tagliaferri, Heather A Harris, Isaac Cohen, Leonard F Bjeldanes, Terence P Speed, Fred Schaufele, Dale C Leitman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0006271&type=printable
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