Nageotte nodules in human dorsal root ganglia reveal neurodegeneration in diabetic peripheral neuropathy

Nageotte nodules in human dorsal root ganglia reveal neurodegeneration in diabetic peripheral neuropathy

Abstract Nageotte nodules, first described in 1922 by Jean Nageotte, are clusters of non-neuronal cells that form after sensory neuron death. Despite their historical recognition, little is known about their molecular identity nor their involvement in neuropathies that involve neuronal loss like dia...

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Main Authors: Stephanie I. Shiers, Khadijah Mazhar, Andi Wangzhou, Rainer Haberberger, Joseph B. Lesnak, Nwasinachi A. Ezeji, Ishwarya Sankaranarayanan, Diana Tavares-Ferreira, Anna Cervantes, Geoffrey Funk, Peter Horton, Erin Vines, Gregory Dussor, Theodore J. Price
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59538-z
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https://doi.org/10.1038/s41467-025-59538-z

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