Antibody-Dependent Cellular Cytotoxicity and NK Cell-Driven Immune Escape in HIV Infection: Implications for HIV Vaccine Development

The HIV-1 genome is malleable and a difficult target tot vaccinate against. It has long been recognised that cytotoxic T lymphocytes and neutralising antibodies readily select for immune escape HIV variants. It is now also clear that NK cells can also select for immune escape. NK cells force immune...

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Bibliographic Details
Main Authors: Gamze Isitman, Ivan Stratov, Stephen J. Kent
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Advances in Virology
Online Access:http://dx.doi.org/10.1155/2012/637208
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