Congenital malformations in children of diabetic mothers in the province of Cienfuegos. 2016-2019
<p><strong>Foundation:</strong> the relationship between developmental alterations and poor glucose control in the pathogenesis of congenital malformations has been demonstrated.<br /><strong>Objective:</strong> to identify congenital malformations in children of...
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| Language: | Spanish |
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Centro Provincial de Información de Ciencias Médicas. Cienfuegos
2024-07-01
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| Series: | Medisur |
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| Online Access: | http://medisur.sld.cu/index.php/medisur/article/view/45220 |
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| author | Fanny Arbolay Sanabria Lázaro Roberto Herrera Fragoso Maylé Santos Solí Gladys Bárbara Barberis Pérez Walkiria Díaz Senra María Soledad Vilches León |
| author_facet | Fanny Arbolay Sanabria Lázaro Roberto Herrera Fragoso Maylé Santos Solí Gladys Bárbara Barberis Pérez Walkiria Díaz Senra María Soledad Vilches León |
| author_sort | Fanny Arbolay Sanabria |
| collection | DOAJ |
| description | <p><strong>Foundation:</strong> the relationship between developmental alterations and poor glucose control in the pathogenesis of congenital malformations has been demonstrated.<br /><strong>Objective:</strong> to identify congenital malformations in children of diabetic mothers.<br /><strong>Methods:</strong> an observational, descriptive cross-sectional study was carried out on diabetic pregnant women whose children had malformations, in the province of Cienfuegos during the period 2016-2019. The variables maternal age, body mass index, type of diabetes, its treatment, type of malformation, ultrasonographic results of the three trimesters of pregnancy, alpha-fetoprotein study and amniocentesis were studied.<br /><strong>Results:</strong> in the studied population the highest percentage of mothers presented gestational diabetes mellitus; Mothers between 20 and 35 years old predominated and a large number of them were overweight. The largest number of birth defects were diagnosed at the second trimester ultrasound (more than 90%). The treatments most used by pregnant women were diet and insulin. Major congenital malformations constituted the largest percentage and the most affected system was the cardiovascular system. <strong><br />Conclusions:</strong> diabetes mellitus and overweight continue to be risk factors for congenital malformations, so reducing them in women of reproductive age and planning pregnancy is important in the prevention of maternal diabetes and its impact on the product of conception.</p> |
| format | Article |
| id | doaj-art-ac343afc3e4f40969343a5f01db9ff02 |
| institution | Kabale University |
| issn | 1727-897X |
| language | Spanish |
| publishDate | 2024-07-01 |
| publisher | Centro Provincial de Información de Ciencias Médicas. Cienfuegos |
| record_format | Article |
| series | Medisur |
| spelling | doaj-art-ac343afc3e4f40969343a5f01db9ff022025-01-30T21:29:03ZspaCentro Provincial de Información de Ciencias Médicas. CienfuegosMedisur1727-897X2024-07-012247187282532Congenital malformations in children of diabetic mothers in the province of Cienfuegos. 2016-2019Fanny Arbolay Sanabria0Lázaro Roberto Herrera Fragoso1Maylé Santos Solí2Gladys Bárbara Barberis Pérez3Walkiria Díaz Senra4María Soledad Vilches León5Universidad de Ciencias Médicas de Cienfuegos. Cuba.Universidad de Ciencias Médicas de Cienfuegos. Cuba.Universidad de Ciencias Médicas de Cienfuegos. Cuba.Universidad de Ciencias Médicas de Cienfuegos. Cuba.Universidad de Ciencias Médicas de Cienfuegos. Cuba.Universidad de Ciencias Médicas de Cienfuegos. Cuba.<p><strong>Foundation:</strong> the relationship between developmental alterations and poor glucose control in the pathogenesis of congenital malformations has been demonstrated.<br /><strong>Objective:</strong> to identify congenital malformations in children of diabetic mothers.<br /><strong>Methods:</strong> an observational, descriptive cross-sectional study was carried out on diabetic pregnant women whose children had malformations, in the province of Cienfuegos during the period 2016-2019. The variables maternal age, body mass index, type of diabetes, its treatment, type of malformation, ultrasonographic results of the three trimesters of pregnancy, alpha-fetoprotein study and amniocentesis were studied.<br /><strong>Results:</strong> in the studied population the highest percentage of mothers presented gestational diabetes mellitus; Mothers between 20 and 35 years old predominated and a large number of them were overweight. The largest number of birth defects were diagnosed at the second trimester ultrasound (more than 90%). The treatments most used by pregnant women were diet and insulin. Major congenital malformations constituted the largest percentage and the most affected system was the cardiovascular system. <strong><br />Conclusions:</strong> diabetes mellitus and overweight continue to be risk factors for congenital malformations, so reducing them in women of reproductive age and planning pregnancy is important in the prevention of maternal diabetes and its impact on the product of conception.</p>http://medisur.sld.cu/index.php/medisur/article/view/45220diabetes gestacionalíndice de masa corporalanomalías congénitasultrasonografía prenatal |
| spellingShingle | Fanny Arbolay Sanabria Lázaro Roberto Herrera Fragoso Maylé Santos Solí Gladys Bárbara Barberis Pérez Walkiria Díaz Senra María Soledad Vilches León Congenital malformations in children of diabetic mothers in the province of Cienfuegos. 2016-2019 Medisur diabetes gestacional índice de masa corporal anomalías congénitas ultrasonografía prenatal |
| title | Congenital malformations in children of diabetic mothers in the province of Cienfuegos. 2016-2019 |
| title_full | Congenital malformations in children of diabetic mothers in the province of Cienfuegos. 2016-2019 |
| title_fullStr | Congenital malformations in children of diabetic mothers in the province of Cienfuegos. 2016-2019 |
| title_full_unstemmed | Congenital malformations in children of diabetic mothers in the province of Cienfuegos. 2016-2019 |
| title_short | Congenital malformations in children of diabetic mothers in the province of Cienfuegos. 2016-2019 |
| title_sort | congenital malformations in children of diabetic mothers in the province of cienfuegos 2016 2019 |
| topic | diabetes gestacional índice de masa corporal anomalías congénitas ultrasonografía prenatal |
| url | http://medisur.sld.cu/index.php/medisur/article/view/45220 |
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