Morroniside ameliorates sevoflurane anesthesia-induced cognitive dysfunction in aged mice through modulating the TLR4/NF-κB pathway

Morroniside ameliorates sevoflurane anesthesia-induced cognitive dysfunction in aged mice through modulating the TLR4/NF-κB pathway

Morroniside (Mor) is a bioactive compound in Cornus officinalis with anti-inflammatory, neuroprotective and antioxidant properties. Prolonged use of the anesthetic sevoflurane (Sev) has been connected to the development postoperative cognitive dysfunction (POCD). This research aims to elucidate the...

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Bibliographic Details
Main Authors: Jianxing Chen, Bo Peng, Wenqian Lin, Yinjun Mao, Yongsheng Wang
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2024-12-01
Series:Biomolecules & Biomedicine
Subjects:
Morroniside
postoperative cognitive dysfunction
sevoflurane
Sev
neuroinflammation
TLR4/NF-κB pathway
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/11433
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