Olfactory Loss in Parkinson's Disease

Impairment of olfaction is a characteristic and early feature of Parkinson's disease. Recent data indicate that >95% of patients with Parkinson's disease present with significant olfactory loss. Deficits in the sense of smell may precede clinical motor symptoms by years and can be used...

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Main Authors: Antje Haehner, Thomas Hummel, Heinz Reichmann
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Parkinson's Disease
Online Access:http://dx.doi.org/10.4061/2011/450939
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author Antje Haehner
Thomas Hummel
Heinz Reichmann
author_facet Antje Haehner
Thomas Hummel
Heinz Reichmann
author_sort Antje Haehner
collection DOAJ
description Impairment of olfaction is a characteristic and early feature of Parkinson's disease. Recent data indicate that >95% of patients with Parkinson's disease present with significant olfactory loss. Deficits in the sense of smell may precede clinical motor symptoms by years and can be used to assess the risk for developing Parkinson's disease in otherwise asymptomatic individuals. This paper summarizes the available information about olfactory function in Parkinson's disease, indicating the advantageous use of olfactory probes in early and differential diagnosis.
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spelling doaj-art-ac216a3e156b4254a804852f0880c84d2025-02-03T01:20:25ZengWileyParkinson's Disease2042-00802011-01-01201110.4061/2011/450939450939Olfactory Loss in Parkinson's DiseaseAntje Haehner0Thomas Hummel1Heinz Reichmann2Department of Otorhinolaryngology and Department of Neurology, Medical School, Dresden University of Technology, Fetscherstraße 74, 01307 Dresden, GermanyDepartment of Otorhinolaryngology, Medical School, Dresden University of Technology, Fetscherstraße 74, 01307 Dresden, GermanyDepartment of Neurology, Medical School, Dresden University of Technology, Fetscherstraße 74, 01307 Dresden, GermanyImpairment of olfaction is a characteristic and early feature of Parkinson's disease. Recent data indicate that >95% of patients with Parkinson's disease present with significant olfactory loss. Deficits in the sense of smell may precede clinical motor symptoms by years and can be used to assess the risk for developing Parkinson's disease in otherwise asymptomatic individuals. This paper summarizes the available information about olfactory function in Parkinson's disease, indicating the advantageous use of olfactory probes in early and differential diagnosis.http://dx.doi.org/10.4061/2011/450939
spellingShingle Antje Haehner
Thomas Hummel
Heinz Reichmann
Olfactory Loss in Parkinson's Disease
Parkinson's Disease
title Olfactory Loss in Parkinson's Disease
title_full Olfactory Loss in Parkinson's Disease
title_fullStr Olfactory Loss in Parkinson's Disease
title_full_unstemmed Olfactory Loss in Parkinson's Disease
title_short Olfactory Loss in Parkinson's Disease
title_sort olfactory loss in parkinson s disease
url http://dx.doi.org/10.4061/2011/450939
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AT thomashummel olfactorylossinparkinsonsdisease
AT heinzreichmann olfactorylossinparkinsonsdisease