An Uncommon Manifestation of a Great Imitator: Gummatous Syphilis of the Liver in an HIV-Positive Patient
Syphilis is a sexually transmitted infection caused by Treponema pallidum. It progresses in phases and undiagnosed disease can cause considerable morbidity. Tertiary syphilis causes the formation of gummas. Liver involvement is rarely described and usually limited to transaminase elevation during pr...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-01-01
|
| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2024/6571155 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832551272514846720 |
|---|---|
| author | Nadia Solomon Tom Heller Tommaso Manciulli Paola Del Giacomo Katleen de Gaetano Donati Enrico Brunetti Francesco Taccari |
| author_facet | Nadia Solomon Tom Heller Tommaso Manciulli Paola Del Giacomo Katleen de Gaetano Donati Enrico Brunetti Francesco Taccari |
| author_sort | Nadia Solomon |
| collection | DOAJ |
| description | Syphilis is a sexually transmitted infection caused by Treponema pallidum. It progresses in phases and undiagnosed disease can cause considerable morbidity. Tertiary syphilis causes the formation of gummas. Liver involvement is rarely described and usually limited to transaminase elevation during primary syphilis. We present a case of tertiary syphilis in an HIV patient. Microbiological, clinical, and radiological information were retrieved from the patient’s record. Gummatous syphilis is rarely described in the literature, and practicing physicians should be aware of its existence and include this manifestation in the differential diagnosis of patients with a positive serology and focal liver lesions. |
| format | Article |
| id | doaj-art-ac152082f0eb47baa6505c2312292ab6 |
| institution | Kabale University |
| issn | 2090-6633 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-ac152082f0eb47baa6505c2312292ab62025-02-03T06:02:22ZengWileyCase Reports in Infectious Diseases2090-66332024-01-01202410.1155/2024/6571155An Uncommon Manifestation of a Great Imitator: Gummatous Syphilis of the Liver in an HIV-Positive PatientNadia Solomon0Tom Heller1Tommaso Manciulli2Paola Del Giacomo3Katleen de Gaetano Donati4Enrico Brunetti5Francesco Taccari6Department of Radiology and Biomedical ImagingLighthouse ClinicDepartment of Experimental and Clinical MedicineInternational Training and Education Center for HealthInternational Training and Education Center for HealthDepartment of Clinical-Surgical, Diagnostic and Pediatric SciencesInternational Training and Education Center for HealthSyphilis is a sexually transmitted infection caused by Treponema pallidum. It progresses in phases and undiagnosed disease can cause considerable morbidity. Tertiary syphilis causes the formation of gummas. Liver involvement is rarely described and usually limited to transaminase elevation during primary syphilis. We present a case of tertiary syphilis in an HIV patient. Microbiological, clinical, and radiological information were retrieved from the patient’s record. Gummatous syphilis is rarely described in the literature, and practicing physicians should be aware of its existence and include this manifestation in the differential diagnosis of patients with a positive serology and focal liver lesions.http://dx.doi.org/10.1155/2024/6571155 |
| spellingShingle | Nadia Solomon Tom Heller Tommaso Manciulli Paola Del Giacomo Katleen de Gaetano Donati Enrico Brunetti Francesco Taccari An Uncommon Manifestation of a Great Imitator: Gummatous Syphilis of the Liver in an HIV-Positive Patient Case Reports in Infectious Diseases |
| title | An Uncommon Manifestation of a Great Imitator: Gummatous Syphilis of the Liver in an HIV-Positive Patient |
| title_full | An Uncommon Manifestation of a Great Imitator: Gummatous Syphilis of the Liver in an HIV-Positive Patient |
| title_fullStr | An Uncommon Manifestation of a Great Imitator: Gummatous Syphilis of the Liver in an HIV-Positive Patient |
| title_full_unstemmed | An Uncommon Manifestation of a Great Imitator: Gummatous Syphilis of the Liver in an HIV-Positive Patient |
| title_short | An Uncommon Manifestation of a Great Imitator: Gummatous Syphilis of the Liver in an HIV-Positive Patient |
| title_sort | uncommon manifestation of a great imitator gummatous syphilis of the liver in an hiv positive patient |
| url | http://dx.doi.org/10.1155/2024/6571155 |
| work_keys_str_mv | AT nadiasolomon anuncommonmanifestationofagreatimitatorgummatoussyphilisoftheliverinanhivpositivepatient AT tomheller anuncommonmanifestationofagreatimitatorgummatoussyphilisoftheliverinanhivpositivepatient AT tommasomanciulli anuncommonmanifestationofagreatimitatorgummatoussyphilisoftheliverinanhivpositivepatient AT paoladelgiacomo anuncommonmanifestationofagreatimitatorgummatoussyphilisoftheliverinanhivpositivepatient AT katleendegaetanodonati anuncommonmanifestationofagreatimitatorgummatoussyphilisoftheliverinanhivpositivepatient AT enricobrunetti anuncommonmanifestationofagreatimitatorgummatoussyphilisoftheliverinanhivpositivepatient AT francescotaccari anuncommonmanifestationofagreatimitatorgummatoussyphilisoftheliverinanhivpositivepatient AT nadiasolomon uncommonmanifestationofagreatimitatorgummatoussyphilisoftheliverinanhivpositivepatient AT tomheller uncommonmanifestationofagreatimitatorgummatoussyphilisoftheliverinanhivpositivepatient AT tommasomanciulli uncommonmanifestationofagreatimitatorgummatoussyphilisoftheliverinanhivpositivepatient AT paoladelgiacomo uncommonmanifestationofagreatimitatorgummatoussyphilisoftheliverinanhivpositivepatient AT katleendegaetanodonati uncommonmanifestationofagreatimitatorgummatoussyphilisoftheliverinanhivpositivepatient AT enricobrunetti uncommonmanifestationofagreatimitatorgummatoussyphilisoftheliverinanhivpositivepatient AT francescotaccari uncommonmanifestationofagreatimitatorgummatoussyphilisoftheliverinanhivpositivepatient |