Pleuroparenchymal Fibroelastosis as a Late-Onset Pulmonary Toxicity after Treatment with Anticancer Chemotherapy for High-Risk Neuroblastoma
Pleuroparenchymal fibroelastosis (PPFE) is a rare, progressive, restrictive lung disease characterized by hypercarbic respiratory failure. In pediatrics, it has been described in patients with a history of malignancy who have received a bone marrow transplant, chemotherapy, or radiotherapy. It is ch...
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2024/4352032 |
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| _version_ | 1832553079062396928 |
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| author | Satoshi Yokoyama Risa Kanai Daisuke Fukao Keigo Hamahata |
| author_facet | Satoshi Yokoyama Risa Kanai Daisuke Fukao Keigo Hamahata |
| author_sort | Satoshi Yokoyama |
| collection | DOAJ |
| description | Pleuroparenchymal fibroelastosis (PPFE) is a rare, progressive, restrictive lung disease characterized by hypercarbic respiratory failure. In pediatrics, it has been described in patients with a history of malignancy who have received a bone marrow transplant, chemotherapy, or radiotherapy. It is characterized by pleural thickening, fibrosis, subpleural elastosis, and intraalveolar collagen deposits. Survival is poor, and the only therapy is lung transplantation. Here, we report a patient who developed PPFE as a late-onset pulmonary toxicity after treatment with anticancer chemotherapy for high-risk neuroblastoma (NB). |
| format | Article |
| id | doaj-art-ac0d3faa0f2f465bb3bd76f1ff71f67d |
| institution | Kabale University |
| issn | 2090-6811 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-ac0d3faa0f2f465bb3bd76f1ff71f67d2025-02-03T05:56:54ZengWileyCase Reports in Pediatrics2090-68112024-01-01202410.1155/2024/4352032Pleuroparenchymal Fibroelastosis as a Late-Onset Pulmonary Toxicity after Treatment with Anticancer Chemotherapy for High-Risk NeuroblastomaSatoshi Yokoyama0Risa Kanai1Daisuke Fukao2Keigo Hamahata3Department of Pediatric SurgeryDepartment of Pediatric SurgeryDepartment of PediatricsDepartment of PediatricsPleuroparenchymal fibroelastosis (PPFE) is a rare, progressive, restrictive lung disease characterized by hypercarbic respiratory failure. In pediatrics, it has been described in patients with a history of malignancy who have received a bone marrow transplant, chemotherapy, or radiotherapy. It is characterized by pleural thickening, fibrosis, subpleural elastosis, and intraalveolar collagen deposits. Survival is poor, and the only therapy is lung transplantation. Here, we report a patient who developed PPFE as a late-onset pulmonary toxicity after treatment with anticancer chemotherapy for high-risk neuroblastoma (NB).http://dx.doi.org/10.1155/2024/4352032 |
| spellingShingle | Satoshi Yokoyama Risa Kanai Daisuke Fukao Keigo Hamahata Pleuroparenchymal Fibroelastosis as a Late-Onset Pulmonary Toxicity after Treatment with Anticancer Chemotherapy for High-Risk Neuroblastoma Case Reports in Pediatrics |
| title | Pleuroparenchymal Fibroelastosis as a Late-Onset Pulmonary Toxicity after Treatment with Anticancer Chemotherapy for High-Risk Neuroblastoma |
| title_full | Pleuroparenchymal Fibroelastosis as a Late-Onset Pulmonary Toxicity after Treatment with Anticancer Chemotherapy for High-Risk Neuroblastoma |
| title_fullStr | Pleuroparenchymal Fibroelastosis as a Late-Onset Pulmonary Toxicity after Treatment with Anticancer Chemotherapy for High-Risk Neuroblastoma |
| title_full_unstemmed | Pleuroparenchymal Fibroelastosis as a Late-Onset Pulmonary Toxicity after Treatment with Anticancer Chemotherapy for High-Risk Neuroblastoma |
| title_short | Pleuroparenchymal Fibroelastosis as a Late-Onset Pulmonary Toxicity after Treatment with Anticancer Chemotherapy for High-Risk Neuroblastoma |
| title_sort | pleuroparenchymal fibroelastosis as a late onset pulmonary toxicity after treatment with anticancer chemotherapy for high risk neuroblastoma |
| url | http://dx.doi.org/10.1155/2024/4352032 |
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