Manual restricted kinematic alignment technique restores postoperative limb alignment in severe knee deformities

Abstract Restricted kinematically aligned total knee arthroplasty (rKA-TKA) for severe deformity in the preoperative hip–knee–ankle angle (HKAA) has gained considerable interest. However, the widespread adoption of rKA-TKA has been limited by its requirement for expensive equipment such as navigatio...

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Main Authors: Masahiro Ishikawa, Masaaki Ishikawa, Hideaki Nagashima, Takafumi Hiranaka
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-13195-w
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author Masahiro Ishikawa
Masaaki Ishikawa
Hideaki Nagashima
Takafumi Hiranaka
author_facet Masahiro Ishikawa
Masaaki Ishikawa
Hideaki Nagashima
Takafumi Hiranaka
author_sort Masahiro Ishikawa
collection DOAJ
description Abstract Restricted kinematically aligned total knee arthroplasty (rKA-TKA) for severe deformity in the preoperative hip–knee–ankle angle (HKAA) has gained considerable interest. However, the widespread adoption of rKA-TKA has been limited by its requirement for expensive equipment such as navigation and robotic surgery systems. In this study, we developed manual rKA-TKA with modified soft tissue-respecting technique and investigated its surgical effects on postoperative HKAA. To achieve this, we examined factors affecting postoperative HKAA. Subsequently, the safe zone-related cut-off values of preoperative HKAA were calculated using the receiver operating characteristic curve, and postoperative HKAA was predicted using a linear regression model (LRM) and generalized additive model (GAM). Preoperative HKAA was identified as a factor influencing postoperative HKAA. The cut-off values of preoperative HKAA were −14 and −15° when the safe zones were defined as ± 1–3 and ± 4–5°, respectively. The GAM was more accurate in predicting the postoperative HKAA than the LRM. Additionally, the GAM showed a potential of falling within ± 5° of the postoperative HKAA, even in patients with preoperative HKAA ≤ − 19°. These findings suggest that manual rKA-TKA can be effective even for patients with severe deformities, providing an accessible alternative to conventional TKA for surgeons at resource-limited institutions.
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spelling doaj-art-abd4a765f14e46d4b45a8e9be74bcc992025-08-20T03:04:39ZengNature PortfolioScientific Reports2045-23222025-07-0115111210.1038/s41598-025-13195-wManual restricted kinematic alignment technique restores postoperative limb alignment in severe knee deformitiesMasahiro Ishikawa0Masaaki Ishikawa1Hideaki Nagashima2Takafumi Hiranaka3Department of Orthopedic Surgery, Nagahama Red Cross HospitalDepartment of Otolaryngology, Head and Neck Surgery, Hyogo Prefectural Amagasaki General Medical CenterDepartment of Orthopedic Surgery, Nagahama Red Cross HospitalDepartment of Orthopedic Surgery and Joint Surgery Centre, Takatsuki General HospitalAbstract Restricted kinematically aligned total knee arthroplasty (rKA-TKA) for severe deformity in the preoperative hip–knee–ankle angle (HKAA) has gained considerable interest. However, the widespread adoption of rKA-TKA has been limited by its requirement for expensive equipment such as navigation and robotic surgery systems. In this study, we developed manual rKA-TKA with modified soft tissue-respecting technique and investigated its surgical effects on postoperative HKAA. To achieve this, we examined factors affecting postoperative HKAA. Subsequently, the safe zone-related cut-off values of preoperative HKAA were calculated using the receiver operating characteristic curve, and postoperative HKAA was predicted using a linear regression model (LRM) and generalized additive model (GAM). Preoperative HKAA was identified as a factor influencing postoperative HKAA. The cut-off values of preoperative HKAA were −14 and −15° when the safe zones were defined as ± 1–3 and ± 4–5°, respectively. The GAM was more accurate in predicting the postoperative HKAA than the LRM. Additionally, the GAM showed a potential of falling within ± 5° of the postoperative HKAA, even in patients with preoperative HKAA ≤ − 19°. These findings suggest that manual rKA-TKA can be effective even for patients with severe deformities, providing an accessible alternative to conventional TKA for surgeons at resource-limited institutions.https://doi.org/10.1038/s41598-025-13195-wTotal knee arthroplastyRestricted kinematically aligned TKAKinematic alignmentHip–knee–ankle angle
spellingShingle Masahiro Ishikawa
Masaaki Ishikawa
Hideaki Nagashima
Takafumi Hiranaka
Manual restricted kinematic alignment technique restores postoperative limb alignment in severe knee deformities
Scientific Reports
Total knee arthroplasty
Restricted kinematically aligned TKA
Kinematic alignment
Hip–knee–ankle angle
title Manual restricted kinematic alignment technique restores postoperative limb alignment in severe knee deformities
title_full Manual restricted kinematic alignment technique restores postoperative limb alignment in severe knee deformities
title_fullStr Manual restricted kinematic alignment technique restores postoperative limb alignment in severe knee deformities
title_full_unstemmed Manual restricted kinematic alignment technique restores postoperative limb alignment in severe knee deformities
title_short Manual restricted kinematic alignment technique restores postoperative limb alignment in severe knee deformities
title_sort manual restricted kinematic alignment technique restores postoperative limb alignment in severe knee deformities
topic Total knee arthroplasty
Restricted kinematically aligned TKA
Kinematic alignment
Hip–knee–ankle angle
url https://doi.org/10.1038/s41598-025-13195-w
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AT masaakiishikawa manualrestrictedkinematicalignmenttechniquerestorespostoperativelimbalignmentinseverekneedeformities
AT hideakinagashima manualrestrictedkinematicalignmenttechniquerestorespostoperativelimbalignmentinseverekneedeformities
AT takafumihiranaka manualrestrictedkinematicalignmenttechniquerestorespostoperativelimbalignmentinseverekneedeformities