Necrotizing Enterocolitis in a 34-Week Premature Infant with COVID-19

Coronavirus disease 2019 (COVID-19) is a viral respiratory infection caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). While SARS-CoV-2 is a leading cause of morbidity and mortality in older adults, COVID-19 also affects newborn infants in nurseries and the Neonatal Intensi...

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Main Authors: Mary K. Mannix, Danielle Blood, Oscar G. Gomez-Duarte, Lauren Davidson
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2021/1442447
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author Mary K. Mannix
Danielle Blood
Oscar G. Gomez-Duarte
Lauren Davidson
author_facet Mary K. Mannix
Danielle Blood
Oscar G. Gomez-Duarte
Lauren Davidson
author_sort Mary K. Mannix
collection DOAJ
description Coronavirus disease 2019 (COVID-19) is a viral respiratory infection caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). While SARS-CoV-2 is a leading cause of morbidity and mortality in older adults, COVID-19 also affects newborn infants in nurseries and the Neonatal Intensive Care Units (NICUs). The majority of infected neonates are believed to acquire SARS-CoV-2 by horizontal transmission, and most of them have asymptomatic or mild symptomatic infections. In rare cases, infants with COVID-19 may have severe complications resulting in death. We report a case of COVID-19 in a premature neonate born at 34 weeks gestational age who presented with hypothermia and respiratory distress and subsequently developed clinical and radiological signs of necrotizing enterocolitis (NEC). The neonate received medical management, including antibiotics, suspension of gastric feeds, and intensive NICU support. The neonate’s clinical condition improved without surgical intervention, and after 10 days of antibiotics and gradual reestablishment of gastric feeds, patient health condition returned to normal, and weeks later, he was discharged home. COVID-19 in infants is frequently asymptomatic or associated with mild disease, and in rare cases, it may be associated with severe gastrointestinal complications including NEC.
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spelling doaj-art-abd277e71ba64a4e98d37feb89c7803d2025-08-20T02:20:13ZengWileyCase Reports in Infectious Diseases2090-66332021-01-01202110.1155/2021/1442447Necrotizing Enterocolitis in a 34-Week Premature Infant with COVID-19Mary K. Mannix0Danielle Blood1Oscar G. Gomez-Duarte2Lauren Davidson3Division of Infectious DiseasesSister’s HospitalDivision of Infectious DiseasesSister’s HospitalCoronavirus disease 2019 (COVID-19) is a viral respiratory infection caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). While SARS-CoV-2 is a leading cause of morbidity and mortality in older adults, COVID-19 also affects newborn infants in nurseries and the Neonatal Intensive Care Units (NICUs). The majority of infected neonates are believed to acquire SARS-CoV-2 by horizontal transmission, and most of them have asymptomatic or mild symptomatic infections. In rare cases, infants with COVID-19 may have severe complications resulting in death. We report a case of COVID-19 in a premature neonate born at 34 weeks gestational age who presented with hypothermia and respiratory distress and subsequently developed clinical and radiological signs of necrotizing enterocolitis (NEC). The neonate received medical management, including antibiotics, suspension of gastric feeds, and intensive NICU support. The neonate’s clinical condition improved without surgical intervention, and after 10 days of antibiotics and gradual reestablishment of gastric feeds, patient health condition returned to normal, and weeks later, he was discharged home. COVID-19 in infants is frequently asymptomatic or associated with mild disease, and in rare cases, it may be associated with severe gastrointestinal complications including NEC.http://dx.doi.org/10.1155/2021/1442447
spellingShingle Mary K. Mannix
Danielle Blood
Oscar G. Gomez-Duarte
Lauren Davidson
Necrotizing Enterocolitis in a 34-Week Premature Infant with COVID-19
Case Reports in Infectious Diseases
title Necrotizing Enterocolitis in a 34-Week Premature Infant with COVID-19
title_full Necrotizing Enterocolitis in a 34-Week Premature Infant with COVID-19
title_fullStr Necrotizing Enterocolitis in a 34-Week Premature Infant with COVID-19
title_full_unstemmed Necrotizing Enterocolitis in a 34-Week Premature Infant with COVID-19
title_short Necrotizing Enterocolitis in a 34-Week Premature Infant with COVID-19
title_sort necrotizing enterocolitis in a 34 week premature infant with covid 19
url http://dx.doi.org/10.1155/2021/1442447
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