Systemic Capillary Leak Syndrome as an Initial Presentation of ALK-Negative Anaplastic Large Cell Lymphoma

Systemic capillary leak syndrome (SCLS) is a rare disease characterized by third spacing of plasma into the extravascular compartment, leading to anasarca, hemoconcentration, and hypovolemic shock. It has been rarely associated with lymphomas, and reports usually indicate that it occurs after antine...

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Main Authors: Laura S. Lourdes, Samer Z. Al-Quran, Nam H. Dang, Merry-Jennifer Markham
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2012/954201
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author Laura S. Lourdes
Samer Z. Al-Quran
Nam H. Dang
Merry-Jennifer Markham
author_facet Laura S. Lourdes
Samer Z. Al-Quran
Nam H. Dang
Merry-Jennifer Markham
author_sort Laura S. Lourdes
collection DOAJ
description Systemic capillary leak syndrome (SCLS) is a rare disease characterized by third spacing of plasma into the extravascular compartment, leading to anasarca, hemoconcentration, and hypovolemic shock. It has been rarely associated with lymphomas, and reports usually indicate that it occurs after antineoplastic treatment. We present the case of a patient with ALK-negative anaplastic large cell lymphoma who presented with SCLS as the initial manifestation of her lymphoma. The SCLS resolved with treatment of the malignancy with steroids and chemotherapy.
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series Case Reports in Hematology
spelling doaj-art-abcbbb824eec4c5c9c1a02c59d254fad2025-02-03T01:02:36ZengWileyCase Reports in Hematology2090-65602090-65792012-01-01201210.1155/2012/954201954201Systemic Capillary Leak Syndrome as an Initial Presentation of ALK-Negative Anaplastic Large Cell LymphomaLaura S. Lourdes0Samer Z. Al-Quran1Nam H. Dang2Merry-Jennifer Markham3Department of Medicine, University of Florida College of Medicine, Gainesville, FL 32610-0278, USADepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL 32610-0278, USADivision of Hematology and Oncology, Department of Medicine, University of Florida College of Medicine, P.O. Box 100278, Gainesville, FL 32610-0278, USADivision of Hematology and Oncology, Department of Medicine, University of Florida College of Medicine, P.O. Box 100278, Gainesville, FL 32610-0278, USASystemic capillary leak syndrome (SCLS) is a rare disease characterized by third spacing of plasma into the extravascular compartment, leading to anasarca, hemoconcentration, and hypovolemic shock. It has been rarely associated with lymphomas, and reports usually indicate that it occurs after antineoplastic treatment. We present the case of a patient with ALK-negative anaplastic large cell lymphoma who presented with SCLS as the initial manifestation of her lymphoma. The SCLS resolved with treatment of the malignancy with steroids and chemotherapy.http://dx.doi.org/10.1155/2012/954201
spellingShingle Laura S. Lourdes
Samer Z. Al-Quran
Nam H. Dang
Merry-Jennifer Markham
Systemic Capillary Leak Syndrome as an Initial Presentation of ALK-Negative Anaplastic Large Cell Lymphoma
Case Reports in Hematology
title Systemic Capillary Leak Syndrome as an Initial Presentation of ALK-Negative Anaplastic Large Cell Lymphoma
title_full Systemic Capillary Leak Syndrome as an Initial Presentation of ALK-Negative Anaplastic Large Cell Lymphoma
title_fullStr Systemic Capillary Leak Syndrome as an Initial Presentation of ALK-Negative Anaplastic Large Cell Lymphoma
title_full_unstemmed Systemic Capillary Leak Syndrome as an Initial Presentation of ALK-Negative Anaplastic Large Cell Lymphoma
title_short Systemic Capillary Leak Syndrome as an Initial Presentation of ALK-Negative Anaplastic Large Cell Lymphoma
title_sort systemic capillary leak syndrome as an initial presentation of alk negative anaplastic large cell lymphoma
url http://dx.doi.org/10.1155/2012/954201
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AT namhdang systemiccapillaryleaksyndromeasaninitialpresentationofalknegativeanaplasticlargecelllymphoma
AT merryjennifermarkham systemiccapillaryleaksyndromeasaninitialpresentationofalknegativeanaplasticlargecelllymphoma