Influence of the COVID-19 pandemic on the prevalence of depression in U.S. adults: evidence from NHANES

Abstract The impact of the COVID-19 pandemic on the epidemiological characteristics of depression among adults in the U.S. remains unclear. This study aims to analyze trends in depression prevalence over time and quantify the effect of the COVID-19 pandemic on its prevalence. Using data from 2007 to...

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Main Authors: Yun Jiang, Wusheng Deng, Mei Zhao
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-87593-5
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author Yun Jiang
Wusheng Deng
Mei Zhao
author_facet Yun Jiang
Wusheng Deng
Mei Zhao
author_sort Yun Jiang
collection DOAJ
description Abstract The impact of the COVID-19 pandemic on the epidemiological characteristics of depression among adults in the U.S. remains unclear. This study aims to analyze trends in depression prevalence over time and quantify the effect of the COVID-19 pandemic on its prevalence. Using data from 2007 to 2023 provided by the National Health and Nutrition Examination Surveys (NHANES), this study examined 36,472 participants. Results revealed an increasing trend in depression prevalence among U.S. adults from 2007 to 2023. Notably, the overall weighted prevalence of depression following the COVID-19 pandemic (12.4%, 95% CI: 10.6-14.1%) was significantly higher than in all years prior to the pandemic. Subgroups such as females, Mexican Americans, and young adults experienced particularly pronounced increases. By analyzing data from two survey cycles close to the onset of the COVID-19 outbreak, the study identified a significant impact of the pandemic on depression prevalence, with an adjusted odds ratio of 1.58 (95% CI: 1.28–1.94). Individuals with lower socioeconomic status and those without pre-existing conditions exhibited greater increases in depression prevalence, whereas the emotional health of individuals who smoke appeared unaffected by the pandemic.
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spelling doaj-art-abbc5010667948c2a9e67ac166577b342025-01-26T12:33:29ZengNature PortfolioScientific Reports2045-23222025-01-0115111010.1038/s41598-025-87593-5Influence of the COVID-19 pandemic on the prevalence of depression in U.S. adults: evidence from NHANESYun Jiang0Wusheng Deng1Mei Zhao2Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Shaoyang UniversityDepartment of Respiratory and Critical Care Medicine, Hunan Provincial People’s Hospital/The First Affiliated Hospital of Hunan Normal UniversitySchool of medicine, Hunan Polytechnic of Environment and BiologyAbstract The impact of the COVID-19 pandemic on the epidemiological characteristics of depression among adults in the U.S. remains unclear. This study aims to analyze trends in depression prevalence over time and quantify the effect of the COVID-19 pandemic on its prevalence. Using data from 2007 to 2023 provided by the National Health and Nutrition Examination Surveys (NHANES), this study examined 36,472 participants. Results revealed an increasing trend in depression prevalence among U.S. adults from 2007 to 2023. Notably, the overall weighted prevalence of depression following the COVID-19 pandemic (12.4%, 95% CI: 10.6-14.1%) was significantly higher than in all years prior to the pandemic. Subgroups such as females, Mexican Americans, and young adults experienced particularly pronounced increases. By analyzing data from two survey cycles close to the onset of the COVID-19 outbreak, the study identified a significant impact of the pandemic on depression prevalence, with an adjusted odds ratio of 1.58 (95% CI: 1.28–1.94). Individuals with lower socioeconomic status and those without pre-existing conditions exhibited greater increases in depression prevalence, whereas the emotional health of individuals who smoke appeared unaffected by the pandemic.https://doi.org/10.1038/s41598-025-87593-5DepressionPrevalenceInfluenceCOVID-19
spellingShingle Yun Jiang
Wusheng Deng
Mei Zhao
Influence of the COVID-19 pandemic on the prevalence of depression in U.S. adults: evidence from NHANES
Scientific Reports
Depression
Prevalence
Influence
COVID-19
title Influence of the COVID-19 pandemic on the prevalence of depression in U.S. adults: evidence from NHANES
title_full Influence of the COVID-19 pandemic on the prevalence of depression in U.S. adults: evidence from NHANES
title_fullStr Influence of the COVID-19 pandemic on the prevalence of depression in U.S. adults: evidence from NHANES
title_full_unstemmed Influence of the COVID-19 pandemic on the prevalence of depression in U.S. adults: evidence from NHANES
title_short Influence of the COVID-19 pandemic on the prevalence of depression in U.S. adults: evidence from NHANES
title_sort influence of the covid 19 pandemic on the prevalence of depression in u s adults evidence from nhanes
topic Depression
Prevalence
Influence
COVID-19
url https://doi.org/10.1038/s41598-025-87593-5
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