TMPRSS2 as a Key Player in Viral Pathogenesis: Influenza and Coronaviruses

TMPRSS2 as a Key Player in Viral Pathogenesis: Influenza and Coronaviruses

TMPRSS2, a human transmembrane protease enzyme, plays a crucial role in the spread of certain viruses, including influenza and coronaviruses. This enzyme promotes viral infection by cleaving viral glycoproteins, which helps viruses like SARS-CoV-2 and influenza A enter cells more effectively. Geneti...

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Bibliographic Details
Main Authors: Gilmara Barros de Lima, Everton Nencioni, Fábio Thimoteo, Camila Perea, Rafaela Fuzaro Alves Pinto, Sergio Daishi Sasaki
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Biomolecules
Subjects:
TMPRSS2
serine proteinase inhibitors
influenza
coronavirus
Online Access:https://www.mdpi.com/2218-273X/15/1/75
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