Bilateral, Simultaneous, Acute Angle Closure Glaucoma in Pseudophakia Induced by Chlorthalidone
Purpose. To report two persons with acute, bilateral, and simultaneous angle closure glaucoma in pseudophakia secondary to uveal effusions induced by administration of chlorthalidone. Methods. Case reports. Results. Bilateral shallow anterior chambers and high intraocular pressure with decline in vi...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Ophthalmological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2016/3713818 |
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| author | Indra Durai Mrunali Mohan Dhavalikar Chandran Prem Anand Venkatraman Ganesh Ramaswami Krishnadas |
| author_facet | Indra Durai Mrunali Mohan Dhavalikar Chandran Prem Anand Venkatraman Ganesh Ramaswami Krishnadas |
| author_sort | Indra Durai |
| collection | DOAJ |
| description | Purpose. To report two persons with acute, bilateral, and simultaneous angle closure glaucoma in pseudophakia secondary to uveal effusions induced by administration of chlorthalidone. Methods. Case reports. Results. Bilateral shallow anterior chambers and high intraocular pressure with decline in visual acuity were reported in two patients within days of intake of chlorthalidone for systemic hypertension. Gonioscopy confirmed appositional angle closure while choroidal detachment and ciliochoroidal detachment were revealed on ultrasonographic studies. Discontinuing chlorthalidone and institution of aqueous suppressants to reduce IOP and cycloplegics reversed angle closure and glaucoma. Conclusions. Reports of angle closure glaucoma in pseudophakic eyes induced by idiosyncratic reaction to chlorthalidone confirms that osmotic changes in the crystalline lens has no role in the pathogenesis of drug induced glaucoma and reaffirms that glaucoma is secondary to ciliochoroidal detachment and ciliary body rotation and edema. |
| format | Article |
| id | doaj-art-ab7ef970d6bc4853b447411f88c86bbe |
| institution | Kabale University |
| issn | 2090-6722 2090-6730 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Ophthalmological Medicine |
| spelling | doaj-art-ab7ef970d6bc4853b447411f88c86bbe2025-02-03T05:44:57ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302016-01-01201610.1155/2016/37138183713818Bilateral, Simultaneous, Acute Angle Closure Glaucoma in Pseudophakia Induced by ChlorthalidoneIndra Durai0Mrunali Mohan Dhavalikar1Chandran Prem Anand2Venkatraman Ganesh3Ramaswami Krishnadas4Aravind Eye Care System, Madurai, IndiaAravind Eye Care System, Coimbatore, IndiaAravind Eye Care System, Coimbatore, IndiaAravind Eye Care System, Coimbatore, IndiaAravind Eye Care System, Madurai, IndiaPurpose. To report two persons with acute, bilateral, and simultaneous angle closure glaucoma in pseudophakia secondary to uveal effusions induced by administration of chlorthalidone. Methods. Case reports. Results. Bilateral shallow anterior chambers and high intraocular pressure with decline in visual acuity were reported in two patients within days of intake of chlorthalidone for systemic hypertension. Gonioscopy confirmed appositional angle closure while choroidal detachment and ciliochoroidal detachment were revealed on ultrasonographic studies. Discontinuing chlorthalidone and institution of aqueous suppressants to reduce IOP and cycloplegics reversed angle closure and glaucoma. Conclusions. Reports of angle closure glaucoma in pseudophakic eyes induced by idiosyncratic reaction to chlorthalidone confirms that osmotic changes in the crystalline lens has no role in the pathogenesis of drug induced glaucoma and reaffirms that glaucoma is secondary to ciliochoroidal detachment and ciliary body rotation and edema.http://dx.doi.org/10.1155/2016/3713818 |
| spellingShingle | Indra Durai Mrunali Mohan Dhavalikar Chandran Prem Anand Venkatraman Ganesh Ramaswami Krishnadas Bilateral, Simultaneous, Acute Angle Closure Glaucoma in Pseudophakia Induced by Chlorthalidone Case Reports in Ophthalmological Medicine |
| title | Bilateral, Simultaneous, Acute Angle Closure Glaucoma in Pseudophakia Induced by Chlorthalidone |
| title_full | Bilateral, Simultaneous, Acute Angle Closure Glaucoma in Pseudophakia Induced by Chlorthalidone |
| title_fullStr | Bilateral, Simultaneous, Acute Angle Closure Glaucoma in Pseudophakia Induced by Chlorthalidone |
| title_full_unstemmed | Bilateral, Simultaneous, Acute Angle Closure Glaucoma in Pseudophakia Induced by Chlorthalidone |
| title_short | Bilateral, Simultaneous, Acute Angle Closure Glaucoma in Pseudophakia Induced by Chlorthalidone |
| title_sort | bilateral simultaneous acute angle closure glaucoma in pseudophakia induced by chlorthalidone |
| url | http://dx.doi.org/10.1155/2016/3713818 |
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