Metagenomic next-generation sequencing-based diagnosis of Pneumocystis jirovecii pneumonia in patients without human immunodeficiency virus infection: A dual-center retrospective propensity matched study

Metagenomic next-generation sequencing-based diagnosis of Pneumocystis jirovecii pneumonia in patients without human immunodeficiency virus infection: A dual-center retrospective propensity matched study

Background: Pneumocystis jirovecii pneumonia (PJP), caused by Pneumocystis jirovecii (PJ), is an opportunistic infection prevalent in clinical settings. However, large-scale studies on the efficacy of metagenomic next-generation sequencing (mNGS)-based diagnosis of PJP in patients without human immu...

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Bibliographic Details
Main Authors: Jin-zhu Wang, Jiang-bo Wang, Ding Yuan, Chang-hua Sun, Lin-lin Hou, Yan Zhang, Xiang-hong Yang, Hong-xiang Xie, Yan-xia Gao
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Journal of Infection and Public Health
Subjects:
Pneumocystis jirovecii pneumonia
Immunodeficiency
Non-HIV patients
Metagenomic next-generation sequencing
Bronchoalveolar lavage fluid
Pathogen
Online Access:http://www.sciencedirect.com/science/article/pii/S1876034125001807
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