HMGCR as a promising molecular target for therapeutic intervention in aortic aneurisms: a mendelian randomization study

Abstract Background Despite the exploration of the connections between serum low-density lipoprotein cholesterol (LDL-C) levels and aneurisms in epidemiological studies, causality remains unclear. Therefore, this study aimed to assess the causal impact of LDL-C-lowering targets (HMGCR, PCSK9, NPC1L1...

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Bibliographic Details
Main Authors: Peng-Fei Zheng, Zhao-Fen Zheng, Zheng-Yu Liu, Jin He, Jing-Jing Rong, Hong-Wei Pan
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Nutrition & Metabolism
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Online Access:https://doi.org/10.1186/s12986-024-00849-1
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