Rat Sarcoma Virus Family Genes in Acute Myeloid Leukemia: Pathogenetic and Clinical Implications

Rat Sarcoma Virus Family Genes in Acute Myeloid Leukemia: Pathogenetic and Clinical Implications

Acute myeloid leukemias (AMLs) comprise a group of genetically heterogeneous hematological malignancies that result in the abnormal growth of leukemic cells and halt the maturation process of normal hematopoietic stem cells. Despite using molecular and cytogenetic risk classification to guide treatm...

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Bibliographic Details
Main Authors: Shaimaa Khattab, Adriatik Berisha, Natalia Baran, Pier Paolo Piccaluga
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Biomedicines
Subjects:
RAS
oncogene
AML
chemoresistance
RAF-MEK-ERK1/2
RAS-like proteins
Online Access:https://www.mdpi.com/2227-9059/13/1/202
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