Myocardial Infarction with Non-Obstructive Coronary Arteries: Contemporary Diagnostic and Management Approaches
Myocardial infarction with non-obstructive coronary arteries (MINOCA) is diagnosed in the absence of anatomically significant stenoses (<50% of lumen diameter) on coronary angiography and characterized by heterogeneity of etiologic factors. Recently, the mechanisms of MINOCA as well as the pe...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Столичная издательская компания
2020-01-01
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| Series: | Рациональная фармакотерапия в кардиологии |
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| Online Access: | https://www.rpcardio.online/jour/article/view/2081 |
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| _version_ | 1849227675485339648 |
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| author | T. H. Hoang P. V. Lazarev V. V. Maiskov A. I. Meray Zh. D. Kobalava |
| author_facet | T. H. Hoang P. V. Lazarev V. V. Maiskov A. I. Meray Zh. D. Kobalava |
| author_sort | T. H. Hoang |
| collection | DOAJ |
| description | Myocardial infarction with non-obstructive coronary arteries (MINOCA) is diagnosed in the absence of anatomically significant stenoses (<50% of lumen diameter) on coronary angiography and characterized by heterogeneity of etiologic factors. Recently, the mechanisms of MINOCA as well as the performance of diagnostic algorithms and therapeutic strategies have been extensively studied. The purpose of this review is to reflect the current concepts regarding the etiology and pathogenesis of MINOCA, diagnostic work-up methods and individualized treatment approaches. The article covers contemporary epidemiologic data, demographic and clinical patients’ characteristics and principal causes of MINOCA. We discuss aspects of disease definition and classification of related conditions involving troponin increase in the presence of normal coronary arteries. The importance of management strategy personalization for individual patients is stressed alongside stratification of risks of recurrent cardiovascular events. This review reflects key points from international consensus statements published by leading experts and suggests promising directions for future research. |
| format | Article |
| id | doaj-art-ab2561b8a6f348c19148e8b1f322551f |
| institution | Kabale University |
| issn | 1819-6446 2225-3653 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj-art-ab2561b8a6f348c19148e8b1f322551f2025-08-23T10:00:31ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532020-01-0115688189110.20996/1819-6446-2019-15-6-881-8911683Myocardial Infarction with Non-Obstructive Coronary Arteries: Contemporary Diagnostic and Management ApproachesT. H. Hoang0P. V. Lazarev1V. V. Maiskov2A. I. Meray3Zh. D. Kobalava4Peoples Friendship University of Russia (RUDN University)Peoples Friendship University of Russia (RUDN University)Peoples Friendship University of Russia (RUDN University); Pirogov Russian National Research Medical University; Vinogradov City Clinical HospitalPeoples Friendship University of Russia (RUDN University); Vinogradov City Clinical HospitalPeoples Friendship University of Russia (RUDN University)Myocardial infarction with non-obstructive coronary arteries (MINOCA) is diagnosed in the absence of anatomically significant stenoses (<50% of lumen diameter) on coronary angiography and characterized by heterogeneity of etiologic factors. Recently, the mechanisms of MINOCA as well as the performance of diagnostic algorithms and therapeutic strategies have been extensively studied. The purpose of this review is to reflect the current concepts regarding the etiology and pathogenesis of MINOCA, diagnostic work-up methods and individualized treatment approaches. The article covers contemporary epidemiologic data, demographic and clinical patients’ characteristics and principal causes of MINOCA. We discuss aspects of disease definition and classification of related conditions involving troponin increase in the presence of normal coronary arteries. The importance of management strategy personalization for individual patients is stressed alongside stratification of risks of recurrent cardiovascular events. This review reflects key points from international consensus statements published by leading experts and suggests promising directions for future research.https://www.rpcardio.online/jour/article/view/2081acute coronary syndromecoronary angiographymyocardial infarction with non-obstructive coronary arteriesatherothrombosiscoronary vasospasmtype 2 myocardial infarction |
| spellingShingle | T. H. Hoang P. V. Lazarev V. V. Maiskov A. I. Meray Zh. D. Kobalava Myocardial Infarction with Non-Obstructive Coronary Arteries: Contemporary Diagnostic and Management Approaches Рациональная фармакотерапия в кардиологии acute coronary syndrome coronary angiography myocardial infarction with non-obstructive coronary arteries atherothrombosis coronary vasospasm type 2 myocardial infarction |
| title | Myocardial Infarction with Non-Obstructive Coronary Arteries: Contemporary Diagnostic and Management Approaches |
| title_full | Myocardial Infarction with Non-Obstructive Coronary Arteries: Contemporary Diagnostic and Management Approaches |
| title_fullStr | Myocardial Infarction with Non-Obstructive Coronary Arteries: Contemporary Diagnostic and Management Approaches |
| title_full_unstemmed | Myocardial Infarction with Non-Obstructive Coronary Arteries: Contemporary Diagnostic and Management Approaches |
| title_short | Myocardial Infarction with Non-Obstructive Coronary Arteries: Contemporary Diagnostic and Management Approaches |
| title_sort | myocardial infarction with non obstructive coronary arteries contemporary diagnostic and management approaches |
| topic | acute coronary syndrome coronary angiography myocardial infarction with non-obstructive coronary arteries atherothrombosis coronary vasospasm type 2 myocardial infarction |
| url | https://www.rpcardio.online/jour/article/view/2081 |
| work_keys_str_mv | AT thhoang myocardialinfarctionwithnonobstructivecoronaryarteriescontemporarydiagnosticandmanagementapproaches AT pvlazarev myocardialinfarctionwithnonobstructivecoronaryarteriescontemporarydiagnosticandmanagementapproaches AT vvmaiskov myocardialinfarctionwithnonobstructivecoronaryarteriescontemporarydiagnosticandmanagementapproaches AT aimeray myocardialinfarctionwithnonobstructivecoronaryarteriescontemporarydiagnosticandmanagementapproaches AT zhdkobalava myocardialinfarctionwithnonobstructivecoronaryarteriescontemporarydiagnosticandmanagementapproaches |