Comparison of Effectiveness and Safety between High-Power Short-Duration Ablation and Conventional Ablation for Atrial Fibrillation: A Systematic Review and Meta-Analysis

Aim. We aimed to evaluate the effectiveness and safety between high-power short-duration (HPSD) radiofrequency ablation (RFA) and conventional RFA in patients with atrial fibrillation (AF). Methods. Studies comparing HPSD and traditional applications in patients undergoing initial catheter ablation...

Full description

Saved in:
Bibliographic Details
Main Authors: Shuyu Jin, Lu Fu, Junrong Jiang, Xingdong Ye, Huiyi Liu, Yanlin Chen, Sijia Pu, Shulin Wu, Yumei Xue
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Journal of Interventional Cardiology
Online Access:http://dx.doi.org/10.1155/2022/6013474
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832549252009558016
author Shuyu Jin
Lu Fu
Junrong Jiang
Xingdong Ye
Huiyi Liu
Yanlin Chen
Sijia Pu
Shulin Wu
Yumei Xue
author_facet Shuyu Jin
Lu Fu
Junrong Jiang
Xingdong Ye
Huiyi Liu
Yanlin Chen
Sijia Pu
Shulin Wu
Yumei Xue
author_sort Shuyu Jin
collection DOAJ
description Aim. We aimed to evaluate the effectiveness and safety between high-power short-duration (HPSD) radiofrequency ablation (RFA) and conventional RFA in patients with atrial fibrillation (AF). Methods. Studies comparing HPSD and traditional applications in patients undergoing initial catheter ablation for atrial fibrillation from inception through December 2021 were searched on Pubmed, Medline, Cochrane, and Clinicaltrials.gov. Results. The meta-analysis included seventeen studies with a total of 4934 patients. HPSD group decreased procedure duration (mean difference (MD) −38.28 min, P<0.001), RF duration (MD −20.51 min, P<0.001), fluoroscopy duration (MD −5.19 min, P<0.001), and acute pulmonary vein reconnection (Odds ratio (OR) 0.40, P<0.001), while improving the freedom from atrial arrhythmia at one year (OR 1.48, 95% confidence interval (CI) 1.12–1.94, P=0.005) and rates of first-pass isolation (OR 8.92, P=0.001). Compared with the conventional group, freedom from atrial arrhythmia at one-year follow-up was higher in the HPSD group without the guidance of AI/LSI (OR 1.66, P=0.01) and studies with a power setting of 40–50 W (OR 1.93, P=0.002). Nevertheless, the two groups had similar effectiveness with a power setting of 50 W in the HPSD RFA (OR 1.10, P=0.52). There was no difference in complications between the two groups (P=0.71). Conclusion. HPSD RFA was associated with shorter procedure duration, higher freedom from atrial arrhythmia, and comparable safety compared to conventional RFA.
format Article
id doaj-art-ab1dec1f0d724abdbddb3d6451b82ce9
institution Kabale University
issn 1540-8183
language English
publishDate 2022-01-01
publisher Wiley
record_format Article
series Journal of Interventional Cardiology
spelling doaj-art-ab1dec1f0d724abdbddb3d6451b82ce92025-02-03T06:11:50ZengWileyJournal of Interventional Cardiology1540-81832022-01-01202210.1155/2022/6013474Comparison of Effectiveness and Safety between High-Power Short-Duration Ablation and Conventional Ablation for Atrial Fibrillation: A Systematic Review and Meta-AnalysisShuyu Jin0Lu Fu1Junrong Jiang2Xingdong Ye3Huiyi Liu4Yanlin Chen5Sijia Pu6Shulin Wu7Yumei Xue8Department of CardiologyDepartment of CardiologyDepartment of CardiologyDepartment of CardiologyDepartment of CardiologyDepartment of CardiologyDepartment of CardiologyDepartment of CardiologyDepartment of CardiologyAim. We aimed to evaluate the effectiveness and safety between high-power short-duration (HPSD) radiofrequency ablation (RFA) and conventional RFA in patients with atrial fibrillation (AF). Methods. Studies comparing HPSD and traditional applications in patients undergoing initial catheter ablation for atrial fibrillation from inception through December 2021 were searched on Pubmed, Medline, Cochrane, and Clinicaltrials.gov. Results. The meta-analysis included seventeen studies with a total of 4934 patients. HPSD group decreased procedure duration (mean difference (MD) −38.28 min, P<0.001), RF duration (MD −20.51 min, P<0.001), fluoroscopy duration (MD −5.19 min, P<0.001), and acute pulmonary vein reconnection (Odds ratio (OR) 0.40, P<0.001), while improving the freedom from atrial arrhythmia at one year (OR 1.48, 95% confidence interval (CI) 1.12–1.94, P=0.005) and rates of first-pass isolation (OR 8.92, P=0.001). Compared with the conventional group, freedom from atrial arrhythmia at one-year follow-up was higher in the HPSD group without the guidance of AI/LSI (OR 1.66, P=0.01) and studies with a power setting of 40–50 W (OR 1.93, P=0.002). Nevertheless, the two groups had similar effectiveness with a power setting of 50 W in the HPSD RFA (OR 1.10, P=0.52). There was no difference in complications between the two groups (P=0.71). Conclusion. HPSD RFA was associated with shorter procedure duration, higher freedom from atrial arrhythmia, and comparable safety compared to conventional RFA.http://dx.doi.org/10.1155/2022/6013474
spellingShingle Shuyu Jin
Lu Fu
Junrong Jiang
Xingdong Ye
Huiyi Liu
Yanlin Chen
Sijia Pu
Shulin Wu
Yumei Xue
Comparison of Effectiveness and Safety between High-Power Short-Duration Ablation and Conventional Ablation for Atrial Fibrillation: A Systematic Review and Meta-Analysis
Journal of Interventional Cardiology
title Comparison of Effectiveness and Safety between High-Power Short-Duration Ablation and Conventional Ablation for Atrial Fibrillation: A Systematic Review and Meta-Analysis
title_full Comparison of Effectiveness and Safety between High-Power Short-Duration Ablation and Conventional Ablation for Atrial Fibrillation: A Systematic Review and Meta-Analysis
title_fullStr Comparison of Effectiveness and Safety between High-Power Short-Duration Ablation and Conventional Ablation for Atrial Fibrillation: A Systematic Review and Meta-Analysis
title_full_unstemmed Comparison of Effectiveness and Safety between High-Power Short-Duration Ablation and Conventional Ablation for Atrial Fibrillation: A Systematic Review and Meta-Analysis
title_short Comparison of Effectiveness and Safety between High-Power Short-Duration Ablation and Conventional Ablation for Atrial Fibrillation: A Systematic Review and Meta-Analysis
title_sort comparison of effectiveness and safety between high power short duration ablation and conventional ablation for atrial fibrillation a systematic review and meta analysis
url http://dx.doi.org/10.1155/2022/6013474
work_keys_str_mv AT shuyujin comparisonofeffectivenessandsafetybetweenhighpowershortdurationablationandconventionalablationforatrialfibrillationasystematicreviewandmetaanalysis
AT lufu comparisonofeffectivenessandsafetybetweenhighpowershortdurationablationandconventionalablationforatrialfibrillationasystematicreviewandmetaanalysis
AT junrongjiang comparisonofeffectivenessandsafetybetweenhighpowershortdurationablationandconventionalablationforatrialfibrillationasystematicreviewandmetaanalysis
AT xingdongye comparisonofeffectivenessandsafetybetweenhighpowershortdurationablationandconventionalablationforatrialfibrillationasystematicreviewandmetaanalysis
AT huiyiliu comparisonofeffectivenessandsafetybetweenhighpowershortdurationablationandconventionalablationforatrialfibrillationasystematicreviewandmetaanalysis
AT yanlinchen comparisonofeffectivenessandsafetybetweenhighpowershortdurationablationandconventionalablationforatrialfibrillationasystematicreviewandmetaanalysis
AT sijiapu comparisonofeffectivenessandsafetybetweenhighpowershortdurationablationandconventionalablationforatrialfibrillationasystematicreviewandmetaanalysis
AT shulinwu comparisonofeffectivenessandsafetybetweenhighpowershortdurationablationandconventionalablationforatrialfibrillationasystematicreviewandmetaanalysis
AT yumeixue comparisonofeffectivenessandsafetybetweenhighpowershortdurationablationandconventionalablationforatrialfibrillationasystematicreviewandmetaanalysis