Serum levels of interleukin-6 are not dependent on the kidney function

Interleukin-6, also named B-cell stimulatory factor, is a glycoprotein with a molecular weight of 26 kDa. Increased serum levels of interleukin-6 (IL-6) are found in several disease conditions. We investigated the importance of a deteriorated kidney function upon IL-6 serum concentrations. No relati...

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Main Author: L. Nässberger
Format: Article
Language:English
Published: Wiley 1992-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/S0962935192000309
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author L. Nässberger
author_facet L. Nässberger
author_sort L. Nässberger
collection DOAJ
description Interleukin-6, also named B-cell stimulatory factor, is a glycoprotein with a molecular weight of 26 kDa. Increased serum levels of interleukin-6 (IL-6) are found in several disease conditions. We investigated the importance of a deteriorated kidney function upon IL-6 serum concentrations. No relation was found between serum levels of IL-6 and s-creatinine, r = 0.004. On the other hand, the serum concentration of complement protein factor D and soluble IL-2 receptor showed a good correlation to s-creatinine, r = 0.92 and 0.79, respectively. In conclusion, serum levels of IL-6 are not dependent upon a reduced kidney function.
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spelling doaj-art-ab00646a13fe4792a7c9366a6c95c1972025-02-03T06:42:19ZengWileyMediators of Inflammation0962-93511466-18611992-01-011319719910.1155/S0962935192000309Serum levels of interleukin-6 are not dependent on the kidney functionL. Nässberger0Department of Medical Microbiology, Clinical Immunology, Lund University, Sölvegatan 23, Lund 223 62, SwedenInterleukin-6, also named B-cell stimulatory factor, is a glycoprotein with a molecular weight of 26 kDa. Increased serum levels of interleukin-6 (IL-6) are found in several disease conditions. We investigated the importance of a deteriorated kidney function upon IL-6 serum concentrations. No relation was found between serum levels of IL-6 and s-creatinine, r = 0.004. On the other hand, the serum concentration of complement protein factor D and soluble IL-2 receptor showed a good correlation to s-creatinine, r = 0.92 and 0.79, respectively. In conclusion, serum levels of IL-6 are not dependent upon a reduced kidney function.http://dx.doi.org/10.1155/S0962935192000309
spellingShingle L. Nässberger
Serum levels of interleukin-6 are not dependent on the kidney function
Mediators of Inflammation
title Serum levels of interleukin-6 are not dependent on the kidney function
title_full Serum levels of interleukin-6 are not dependent on the kidney function
title_fullStr Serum levels of interleukin-6 are not dependent on the kidney function
title_full_unstemmed Serum levels of interleukin-6 are not dependent on the kidney function
title_short Serum levels of interleukin-6 are not dependent on the kidney function
title_sort serum levels of interleukin 6 are not dependent on the kidney function
url http://dx.doi.org/10.1155/S0962935192000309
work_keys_str_mv AT lnassberger serumlevelsofinterleukin6arenotdependentonthekidneyfunction