Serum levels of interleukin-6 are not dependent on the kidney function
Interleukin-6, also named B-cell stimulatory factor, is a glycoprotein with a molecular weight of 26 kDa. Increased serum levels of interleukin-6 (IL-6) are found in several disease conditions. We investigated the importance of a deteriorated kidney function upon IL-6 serum concentrations. No relati...
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Format: | Article |
Language: | English |
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Wiley
1992-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/S0962935192000309 |
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author | L. Nässberger |
author_facet | L. Nässberger |
author_sort | L. Nässberger |
collection | DOAJ |
description | Interleukin-6, also named B-cell stimulatory factor, is a glycoprotein with a molecular weight of 26 kDa. Increased serum levels of interleukin-6 (IL-6) are found in several disease conditions. We investigated the importance of a deteriorated kidney function upon IL-6 serum concentrations. No relation was found between serum levels of IL-6 and s-creatinine, r = 0.004. On the other hand, the serum concentration of complement protein factor D and soluble IL-2 receptor showed a good correlation to s-creatinine, r = 0.92 and 0.79, respectively. In conclusion, serum levels of IL-6 are not dependent upon a reduced kidney function. |
format | Article |
id | doaj-art-ab00646a13fe4792a7c9366a6c95c197 |
institution | Kabale University |
issn | 0962-9351 1466-1861 |
language | English |
publishDate | 1992-01-01 |
publisher | Wiley |
record_format | Article |
series | Mediators of Inflammation |
spelling | doaj-art-ab00646a13fe4792a7c9366a6c95c1972025-02-03T06:42:19ZengWileyMediators of Inflammation0962-93511466-18611992-01-011319719910.1155/S0962935192000309Serum levels of interleukin-6 are not dependent on the kidney functionL. Nässberger0Department of Medical Microbiology, Clinical Immunology, Lund University, Sölvegatan 23, Lund 223 62, SwedenInterleukin-6, also named B-cell stimulatory factor, is a glycoprotein with a molecular weight of 26 kDa. Increased serum levels of interleukin-6 (IL-6) are found in several disease conditions. We investigated the importance of a deteriorated kidney function upon IL-6 serum concentrations. No relation was found between serum levels of IL-6 and s-creatinine, r = 0.004. On the other hand, the serum concentration of complement protein factor D and soluble IL-2 receptor showed a good correlation to s-creatinine, r = 0.92 and 0.79, respectively. In conclusion, serum levels of IL-6 are not dependent upon a reduced kidney function.http://dx.doi.org/10.1155/S0962935192000309 |
spellingShingle | L. Nässberger Serum levels of interleukin-6 are not dependent on the kidney function Mediators of Inflammation |
title | Serum levels of interleukin-6 are not dependent on the kidney function |
title_full | Serum levels of interleukin-6 are not dependent on the kidney function |
title_fullStr | Serum levels of interleukin-6 are not dependent on the kidney function |
title_full_unstemmed | Serum levels of interleukin-6 are not dependent on the kidney function |
title_short | Serum levels of interleukin-6 are not dependent on the kidney function |
title_sort | serum levels of interleukin 6 are not dependent on the kidney function |
url | http://dx.doi.org/10.1155/S0962935192000309 |
work_keys_str_mv | AT lnassberger serumlevelsofinterleukin6arenotdependentonthekidneyfunction |