Emerging strategies to overcome ovarian cancer: advances in immunotherapy
Ovarian cancer is the second most common malignant neoplasm of gynecological origin and the leading cause of death from cancer in the female reproductive system worldwide. This scenario is largely due to late diagnoses, often in advanced stages, and the development of chemoresistance by cancer cells...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-11-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2024.1490896/full |
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| author | Tatiana Massariol Pimenta Josiany Carlos de Souza Bárbara da Silva Martins Solenny Maria Silva Butzene José Matheus Simões Padilha Milleny Ganho Marçal Guilherme dos Santos Elias Leticia Batista Azevedo Rangel Leticia Batista Azevedo Rangel Leticia Batista Azevedo Rangel |
| author_facet | Tatiana Massariol Pimenta Josiany Carlos de Souza Bárbara da Silva Martins Solenny Maria Silva Butzene José Matheus Simões Padilha Milleny Ganho Marçal Guilherme dos Santos Elias Leticia Batista Azevedo Rangel Leticia Batista Azevedo Rangel Leticia Batista Azevedo Rangel |
| author_sort | Tatiana Massariol Pimenta |
| collection | DOAJ |
| description | Ovarian cancer is the second most common malignant neoplasm of gynecological origin and the leading cause of death from cancer in the female reproductive system worldwide. This scenario is largely due to late diagnoses, often in advanced stages, and the development of chemoresistance by cancer cells. These challenges highlight the need for alternative treatments, with immunotherapy being a promising option. Cancer immunotherapy involves triggering an anti-tumor immune response and developing immunological memory to eliminate malignant cells, prevent recurrence, and inhibit metastasis. Some ongoing research investigate potentially immunological advancements in the field of cancer vaccines, immune checkpoint blockade, CAR-T cell, and other strategies. |
| format | Article |
| id | doaj-art-aae7bd66ae1a4b2ea7dd3158ff94c607 |
| institution | OA Journals |
| issn | 1663-9812 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj-art-aae7bd66ae1a4b2ea7dd3158ff94c6072025-08-20T02:18:58ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122024-11-011510.3389/fphar.2024.14908961490896Emerging strategies to overcome ovarian cancer: advances in immunotherapyTatiana Massariol Pimenta0Josiany Carlos de Souza1Bárbara da Silva Martins2Solenny Maria Silva Butzene3José Matheus Simões Padilha4Milleny Ganho Marçal5Guilherme dos Santos Elias6Leticia Batista Azevedo Rangel7Leticia Batista Azevedo Rangel8Leticia Batista Azevedo Rangel9Department of Pharmaceutical Sciences, Health Sciences Center, Federal University of Espírito Santo, Vitória, Espírito Santo, BrazilBiotechnology Program/RENORBIO, Health Sciences Center, Federal University of Espírito Santo, Vitória, Espírito Santo, BrazilDepartment of Pharmaceutical Sciences, Health Sciences Center, Federal University of Espírito Santo, Vitória, Espírito Santo, BrazilDepartment of Pharmaceutical Sciences, Health Sciences Center, Federal University of Espírito Santo, Vitória, Espírito Santo, BrazilDepartment of Pharmaceutical Sciences, Health Sciences Center, Federal University of Espírito Santo, Vitória, Espírito Santo, BrazilDepartment of Pharmaceutical Sciences, Health Sciences Center, Federal University of Espírito Santo, Vitória, Espírito Santo, BrazilBiochemistry Program, Health Sciences Center, Federal University of Espírito Santo, Vitória, Espírito Santo, BrazilDepartment of Pharmaceutical Sciences, Health Sciences Center, Federal University of Espírito Santo, Vitória, Espírito Santo, BrazilBiotechnology Program/RENORBIO, Health Sciences Center, Federal University of Espírito Santo, Vitória, Espírito Santo, BrazilBiochemistry Program, Health Sciences Center, Federal University of Espírito Santo, Vitória, Espírito Santo, BrazilOvarian cancer is the second most common malignant neoplasm of gynecological origin and the leading cause of death from cancer in the female reproductive system worldwide. This scenario is largely due to late diagnoses, often in advanced stages, and the development of chemoresistance by cancer cells. These challenges highlight the need for alternative treatments, with immunotherapy being a promising option. Cancer immunotherapy involves triggering an anti-tumor immune response and developing immunological memory to eliminate malignant cells, prevent recurrence, and inhibit metastasis. Some ongoing research investigate potentially immunological advancements in the field of cancer vaccines, immune checkpoint blockade, CAR-T cell, and other strategies.https://www.frontiersin.org/articles/10.3389/fphar.2024.1490896/fullovarian cancerimmunotherapycancer vaccinesCAR-T cell therapyantibody therapy |
| spellingShingle | Tatiana Massariol Pimenta Josiany Carlos de Souza Bárbara da Silva Martins Solenny Maria Silva Butzene José Matheus Simões Padilha Milleny Ganho Marçal Guilherme dos Santos Elias Leticia Batista Azevedo Rangel Leticia Batista Azevedo Rangel Leticia Batista Azevedo Rangel Emerging strategies to overcome ovarian cancer: advances in immunotherapy Frontiers in Pharmacology ovarian cancer immunotherapy cancer vaccines CAR-T cell therapy antibody therapy |
| title | Emerging strategies to overcome ovarian cancer: advances in immunotherapy |
| title_full | Emerging strategies to overcome ovarian cancer: advances in immunotherapy |
| title_fullStr | Emerging strategies to overcome ovarian cancer: advances in immunotherapy |
| title_full_unstemmed | Emerging strategies to overcome ovarian cancer: advances in immunotherapy |
| title_short | Emerging strategies to overcome ovarian cancer: advances in immunotherapy |
| title_sort | emerging strategies to overcome ovarian cancer advances in immunotherapy |
| topic | ovarian cancer immunotherapy cancer vaccines CAR-T cell therapy antibody therapy |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2024.1490896/full |
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