Cadmium targeting transcription factor EB to inhibit autophagy-lysosome function contributes to acute kidney injury

Cadmium targeting transcription factor EB to inhibit autophagy-lysosome function contributes to acute kidney injury

Introduction: Environmental and occupational exposure to cadmium (Cd) has been shown to cause acute kidney injury (AKI). Previous studies have demonstrated that autophagy inhibition and lysosomal dysfunction are important mechanisms of Cd-induced AKI. Objectives: Transcription factor EB (TFEB) is a...

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Bibliographic Details
Main Authors: Peng-Fei Dong, Tian-Bin Liu, Kai Chen, Dan Li, Yue Li, Cai-Yu Lian, Zhen-Yong Wang, Lin Wang
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Journal of Advanced Research
Subjects:
Cadmium
transcription factor EB
Acute kidney injury
Autophagy
Lysosome
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123224002972
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