Infection remains a leading cause of neonatal mortality among infants delivered at a tertiary hospital in Karachi, Pakistan

Introduction: The current cohort study was conducted to determine the frequency and compare the mortality rate with associated characteristics among low birth weight and normal birth weight infants during the neonatal period at a tertiary healthcare facility, Karachi. Methodology: Close-ended struc...

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Main Authors: Muhammad Ayaz Mustufa, Razia Korejo, Anjum Shahid, Sadia Nasim
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2014-11-01
Series:Journal of Infection in Developing Countries
Subjects:
Online Access:https://jidc.org/index.php/journal/article/view/3569
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author Muhammad Ayaz Mustufa
Razia Korejo
Anjum Shahid
Sadia Nasim
author_facet Muhammad Ayaz Mustufa
Razia Korejo
Anjum Shahid
Sadia Nasim
author_sort Muhammad Ayaz Mustufa
collection DOAJ
description Introduction: The current cohort study was conducted to determine the frequency and compare the mortality rate with associated characteristics among low birth weight and normal birth weight infants during the neonatal period at a tertiary healthcare facility, Karachi. Methodology: Close-ended structured questionnaires were used to collect information from the parents of 500 registered neonates at the time of birth. Follow-ups by phone on the 28th day of life were done to determine the mortality among low birth weight and normal birth weight babies during the neonatal period. Results: The neonatal mortality rate ranged from as low as 2.4% in the normal birth weight and 16.4% in the low birth weight categories to as high as 96% in the very low birth weight category. Respiratory distress syndrome (24.2%) and sepsis (18.2%) were reported as the leading causes of neonatal deaths. The babies’ lengths of stay ranged from 2 to 24 hours, and around 90% of neonatal deaths were reported in the first seven days of life. More than 6% of neonates died at home, and 7.6% of the deceased babies did not visit any healthcare facility or doctor before their death. In the 12–15 hours before their deaths, 13.6% of the deceased babies had been unattended. Around 90% of the deceased babies were referred from a doctor or healthcare facility. Conclusions: The present estimates of neonatal mortality are very high among low birth weight and very low birth weight categories. Infectious diseases, including respiratory distress syndrome (24.2%) and sepsis (18.2%), were leading causes of neonatal deaths.
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spelling doaj-art-aabc75b23d8a4cfdbb3554f87ffcb1aa2025-08-20T02:27:18ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802014-11-0181110.3855/jidc.3569Infection remains a leading cause of neonatal mortality among infants delivered at a tertiary hospital in Karachi, PakistanMuhammad Ayaz Mustufa0Razia Korejo1Anjum Shahid2Sadia Nasim3PMRC, Specialized Research Centre on Child Health, National Institute of Child Health, Karachi, PakistanJinnah Postgraduate Medical Centre, Karachi, PakistanPMRC, Specialized Research Centre on Child Health, National Institute of Child Health, Karachi, PakistanPMRC, Specialized Research Centre on Child Health, National Institute of Child Health, Karachi, PakistanIntroduction: The current cohort study was conducted to determine the frequency and compare the mortality rate with associated characteristics among low birth weight and normal birth weight infants during the neonatal period at a tertiary healthcare facility, Karachi. Methodology: Close-ended structured questionnaires were used to collect information from the parents of 500 registered neonates at the time of birth. Follow-ups by phone on the 28th day of life were done to determine the mortality among low birth weight and normal birth weight babies during the neonatal period. Results: The neonatal mortality rate ranged from as low as 2.4% in the normal birth weight and 16.4% in the low birth weight categories to as high as 96% in the very low birth weight category. Respiratory distress syndrome (24.2%) and sepsis (18.2%) were reported as the leading causes of neonatal deaths. The babies’ lengths of stay ranged from 2 to 24 hours, and around 90% of neonatal deaths were reported in the first seven days of life. More than 6% of neonates died at home, and 7.6% of the deceased babies did not visit any healthcare facility or doctor before their death. In the 12–15 hours before their deaths, 13.6% of the deceased babies had been unattended. Around 90% of the deceased babies were referred from a doctor or healthcare facility. Conclusions: The present estimates of neonatal mortality are very high among low birth weight and very low birth weight categories. Infectious diseases, including respiratory distress syndrome (24.2%) and sepsis (18.2%), were leading causes of neonatal deaths. https://jidc.org/index.php/journal/article/view/3569normal birth weightlow birth weightmortality
spellingShingle Muhammad Ayaz Mustufa
Razia Korejo
Anjum Shahid
Sadia Nasim
Infection remains a leading cause of neonatal mortality among infants delivered at a tertiary hospital in Karachi, Pakistan
Journal of Infection in Developing Countries
normal birth weight
low birth weight
mortality
title Infection remains a leading cause of neonatal mortality among infants delivered at a tertiary hospital in Karachi, Pakistan
title_full Infection remains a leading cause of neonatal mortality among infants delivered at a tertiary hospital in Karachi, Pakistan
title_fullStr Infection remains a leading cause of neonatal mortality among infants delivered at a tertiary hospital in Karachi, Pakistan
title_full_unstemmed Infection remains a leading cause of neonatal mortality among infants delivered at a tertiary hospital in Karachi, Pakistan
title_short Infection remains a leading cause of neonatal mortality among infants delivered at a tertiary hospital in Karachi, Pakistan
title_sort infection remains a leading cause of neonatal mortality among infants delivered at a tertiary hospital in karachi pakistan
topic normal birth weight
low birth weight
mortality
url https://jidc.org/index.php/journal/article/view/3569
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AT raziakorejo infectionremainsaleadingcauseofneonatalmortalityamonginfantsdeliveredatatertiaryhospitalinkarachipakistan
AT anjumshahid infectionremainsaleadingcauseofneonatalmortalityamonginfantsdeliveredatatertiaryhospitalinkarachipakistan
AT sadianasim infectionremainsaleadingcauseofneonatalmortalityamonginfantsdeliveredatatertiaryhospitalinkarachipakistan