First Presentation of Systemic Lupus Erythematosus in a 24-Year-Old Male following mRNA COVID-19 Vaccine
The SARS-CoV-2 viral pandemic has had an immeasurable global impact, resulting in over 5 million deaths worldwide. Numerous vaccines were developed in an attempt to quell viral dissemination and reduce symptom severity among those infected. Systemic lupus erythematosus (SLE) is an autoimmune disease...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2022/9698138 |
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| author | Yael Raviv Batya Betesh-Abay Yuliya Valdman-Grinshpoun Liora Boehm-Cohen Michael Kassirer Iftach Sagy |
| author_facet | Yael Raviv Batya Betesh-Abay Yuliya Valdman-Grinshpoun Liora Boehm-Cohen Michael Kassirer Iftach Sagy |
| author_sort | Yael Raviv |
| collection | DOAJ |
| description | The SARS-CoV-2 viral pandemic has had an immeasurable global impact, resulting in over 5 million deaths worldwide. Numerous vaccines were developed in an attempt to quell viral dissemination and reduce symptom severity among those infected. Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of antinuclear autoantibodies (ANAs) with heterogenic clinical manifestations, secondary to immune complex deposition in a multitude of organ systems. There are scarcely reported cases of SLE development following COVID-19 mRNA vaccination. We present a case of a 24-year-old male without preexisting conditions or family history of autoimmune disorders, presenting with SLE following the first dose of the SARS-CoV-2 Pfizer-BioNTech mRNA vaccine. |
| format | Article |
| id | doaj-art-aaaa1535ad3848e5a5856ca1696547eb |
| institution | Kabale University |
| issn | 2090-6897 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-aaaa1535ad3848e5a5856ca1696547eb2025-02-03T06:05:31ZengWileyCase Reports in Rheumatology2090-68972022-01-01202210.1155/2022/9698138First Presentation of Systemic Lupus Erythematosus in a 24-Year-Old Male following mRNA COVID-19 VaccineYael Raviv0Batya Betesh-Abay1Yuliya Valdman-Grinshpoun2Liora Boehm-Cohen3Michael Kassirer4Iftach Sagy5Pulmonary InstituteRecanati School for Community Health ProfessionsDepartment of DermatologyPulmonary InstitutePulmonary InstituteRheumatology Unit and Clinical Research CenterThe SARS-CoV-2 viral pandemic has had an immeasurable global impact, resulting in over 5 million deaths worldwide. Numerous vaccines were developed in an attempt to quell viral dissemination and reduce symptom severity among those infected. Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of antinuclear autoantibodies (ANAs) with heterogenic clinical manifestations, secondary to immune complex deposition in a multitude of organ systems. There are scarcely reported cases of SLE development following COVID-19 mRNA vaccination. We present a case of a 24-year-old male without preexisting conditions or family history of autoimmune disorders, presenting with SLE following the first dose of the SARS-CoV-2 Pfizer-BioNTech mRNA vaccine.http://dx.doi.org/10.1155/2022/9698138 |
| spellingShingle | Yael Raviv Batya Betesh-Abay Yuliya Valdman-Grinshpoun Liora Boehm-Cohen Michael Kassirer Iftach Sagy First Presentation of Systemic Lupus Erythematosus in a 24-Year-Old Male following mRNA COVID-19 Vaccine Case Reports in Rheumatology |
| title | First Presentation of Systemic Lupus Erythematosus in a 24-Year-Old Male following mRNA COVID-19 Vaccine |
| title_full | First Presentation of Systemic Lupus Erythematosus in a 24-Year-Old Male following mRNA COVID-19 Vaccine |
| title_fullStr | First Presentation of Systemic Lupus Erythematosus in a 24-Year-Old Male following mRNA COVID-19 Vaccine |
| title_full_unstemmed | First Presentation of Systemic Lupus Erythematosus in a 24-Year-Old Male following mRNA COVID-19 Vaccine |
| title_short | First Presentation of Systemic Lupus Erythematosus in a 24-Year-Old Male following mRNA COVID-19 Vaccine |
| title_sort | first presentation of systemic lupus erythematosus in a 24 year old male following mrna covid 19 vaccine |
| url | http://dx.doi.org/10.1155/2022/9698138 |
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