Predicting reperfusion injury and functional status after stroke using blood biomarkers: the STROKELABED study

Predicting reperfusion injury and functional status after stroke using blood biomarkers: the STROKELABED study

Abstract Background Ischemic stroke is a leading cause of disability and mortality, particularly among the elderly. Recanalization therapies, including thrombolysis and thrombectomy, are essential for restoring blood flow and saving ischemic tissue. However, these interventions may trigger reperfusi...

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Main Authors: Alessia Vignoli, Elena Sticchi, Benedetta Piccardi, Vanessa Palumbo, Cristina Sarti, Alessandro Sodero, Francesco Arba, Enrico Fainardi, Anna Maria Gori, Betti Giusti, Ada Kura, Leonardo Tenori, Marzia Baldereschi
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Journal of Translational Medicine
Subjects:
Stroke
Biomarkers
Inflammation
Blood brain barrier
Cerebral edema
Functional outcome
Online Access:https://doi.org/10.1186/s12967-025-06498-z
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