Nanotechnology’s impact on disease management: A review of applications in non-communicable and communicable diseases

Despite the improvements that humans have experienced in their lifestyle and the technological developments applied to new and better treatments for the most diverse pathologies, there are still many diseases that affect human health with high levels of mortality. The WHO classifies diseases as Non-...

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Main Authors: Exequiel David Giorgi, Federico Gastón Baudou, María Eugenia Díaz, Liliana Noemí Guerra, Pablo Luis Santo Orihuela, Gorka Orive, Martin Federico Desimone, Mauricio César De Marzi
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Next Nanotechnology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2949829525001019
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Summary:Despite the improvements that humans have experienced in their lifestyle and the technological developments applied to new and better treatments for the most diverse pathologies, there are still many diseases that affect human health with high levels of mortality. The WHO classifies diseases as Non-Communicable Diseases, Communicable Diseases and Injuries. Non-communicable diseases, also known as chronic diseases, are responsible for about 70 % of all deaths in the world. Of these, three quarters occur in low- and middle-income countries. Communicable diseases are infectious diseases where not only the development of treatments but also vaccines, becomes imperative to have tools to combat these diseases. In this context, nanomedicine uses nanomaterials as novel tools for disease treatment, taking advantage of engineered nanomaterials’ attractive properties such as drug delivery of therapeutic agents and targeting to specific tissues. These nanomaterials can avoid or diminish specific immune reactions that could be detrimental to patients’ health. This work presents a comprehensive analysis of the literature on recent advances in nanotechnology to combat representative diseases, based on the WHO classification. In short, we compiled the most relevant bibliography with an impact on the use of nanoparticles in non-communicable diseases (cancer, diabetes mellitus, endocrine, blood and immunological disorders, cardiovascular diseases and respiratory diseases), communicable diseases (bacterial, fungi, parasites and virus infections) and also in the treatment of injuries that may or not be related to the previous ones.
ISSN:2949-8295