Residual transmission of schistosomiasis in Ndikinimeki Health District (Centre Region, Cameroon) despite implementation of complementary control strategies: Prospects for elimination
Schistosomiasis control currently relies on school-based preventive chemotherapy (PC) with praziquantel, which has been proven, unfortunately, insufficient to interrupt disease transmission in areas with persistent transmission. In the Ndikinimeki Health District (Centre Region, Cameroon), complemen...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-02-01
|
| Series: | Parasite Epidemiology and Control |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405673125000030 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832087567732834304 |
|---|---|
| author | Hervé Kengne Fogang Hugues C. Nana Djeunga Alvine C. Kengne-Fokam Murielle C. Tchami Mbagnia Flobert Njiokou Dickson S. Nsagha Emmanuel Yenshu Joseph Kamgno |
| author_facet | Hervé Kengne Fogang Hugues C. Nana Djeunga Alvine C. Kengne-Fokam Murielle C. Tchami Mbagnia Flobert Njiokou Dickson S. Nsagha Emmanuel Yenshu Joseph Kamgno |
| author_sort | Hervé Kengne Fogang |
| collection | DOAJ |
| description | Schistosomiasis control currently relies on school-based preventive chemotherapy (PC) with praziquantel, which has been proven, unfortunately, insufficient to interrupt disease transmission in areas with persistent transmission. In the Ndikinimeki Health District (Centre Region, Cameroon), complementary strategies (community-based preventive chemotherapy, water sanitation, hygiene, and health education) have also been implemented to accelerate the interruption of schistosomiasis transmission in this focus. The assessment of the impact of this package of interventions revealed that only a few individuals were still infected with Schistosoma mansoni. This study, therefore, aimed to investigate whether schistosomiasis transmission has been interrupted in the Ndikinimeki Health District by assessing the infection among the population of snails, intermediate hosts of schistosomiasis. A cross-sectional malacological survey was conducted in four health areas of the Ndikinimeki Health District using a standardized technique. Collected snails were transported to the laboratory, where they were identified and exposed to sunlight for cercarial shedding. Overall, 350 snails intermediate hosts of schistosomes were collected in 32 sampling sites. A total of 330 (94.3 %) were identified as Biomphalaria pfeifferi and Biomphalaria camerunensis, and 20 (5.7 %) as Bulinus forskalii. Of the 154 snails that survived during 30 days of follow-up, 16 (10.4 %; 95 % CI: 6.5–16.2) shed cercariae, the infection rate being quite heterogeneous between snails' species and communities. This study revealed a residual transmission of schistosomiasis in the snail populations, emphasizing the need for snail control to complement current interventions and accelerate schistosomiasis transmission interruption. |
| format | Article |
| id | doaj-art-aa8b25c76a9d4410b19a6aa62207ccce |
| institution | Kabale University |
| issn | 2405-6731 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Parasite Epidemiology and Control |
| spelling | doaj-art-aa8b25c76a9d4410b19a6aa62207ccce2025-02-06T05:12:31ZengElsevierParasite Epidemiology and Control2405-67312025-02-0128e00410Residual transmission of schistosomiasis in Ndikinimeki Health District (Centre Region, Cameroon) despite implementation of complementary control strategies: Prospects for eliminationHervé Kengne Fogang0Hugues C. Nana Djeunga1Alvine C. Kengne-Fokam2Murielle C. Tchami Mbagnia3Flobert Njiokou4Dickson S. Nsagha5Emmanuel Yenshu6Joseph Kamgno7Department of Public Health and Hygiene, Faculty of Health Sciences, University of Buea, Buea, Cameroon; Higher Institute for Scientific and Medical Research (ISM), Yaoundé, Cameroon; Corresponding authors at: Higher Institute for Scientific and Medical Research (ISM), Yaoundé, Cameroon.Higher Institute for Scientific and Medical Research (ISM), Yaoundé, Cameroon; Corresponding authors at: Higher Institute for Scientific and Medical Research (ISM), Yaoundé, Cameroon.Parasitology and Ecology Laboratory, Department of Animal Biology and Physiology, Faculty of Science, University of Yaoundé I, Yaoundé, CameroonParasitology and Ecology Laboratory, Department of Animal Biology and Physiology, Faculty of Science, University of Yaoundé I, Yaoundé, CameroonParasitology and Ecology Laboratory, Department of Animal Biology and Physiology, Faculty of Science, University of Yaoundé I, Yaoundé, CameroonDepartment of Public Health and Hygiene, Faculty of Health Sciences, University of Buea, Buea, CameroonDepartement of Sociology and Anthropology, Faculty of Social Science and Management, University of Buea, Buea, CameroonHigher Institute for Scientific and Medical Research (ISM), Yaoundé, Cameroon; Department of Public Health, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, CameroonSchistosomiasis control currently relies on school-based preventive chemotherapy (PC) with praziquantel, which has been proven, unfortunately, insufficient to interrupt disease transmission in areas with persistent transmission. In the Ndikinimeki Health District (Centre Region, Cameroon), complementary strategies (community-based preventive chemotherapy, water sanitation, hygiene, and health education) have also been implemented to accelerate the interruption of schistosomiasis transmission in this focus. The assessment of the impact of this package of interventions revealed that only a few individuals were still infected with Schistosoma mansoni. This study, therefore, aimed to investigate whether schistosomiasis transmission has been interrupted in the Ndikinimeki Health District by assessing the infection among the population of snails, intermediate hosts of schistosomiasis. A cross-sectional malacological survey was conducted in four health areas of the Ndikinimeki Health District using a standardized technique. Collected snails were transported to the laboratory, where they were identified and exposed to sunlight for cercarial shedding. Overall, 350 snails intermediate hosts of schistosomes were collected in 32 sampling sites. A total of 330 (94.3 %) were identified as Biomphalaria pfeifferi and Biomphalaria camerunensis, and 20 (5.7 %) as Bulinus forskalii. Of the 154 snails that survived during 30 days of follow-up, 16 (10.4 %; 95 % CI: 6.5–16.2) shed cercariae, the infection rate being quite heterogeneous between snails' species and communities. This study revealed a residual transmission of schistosomiasis in the snail populations, emphasizing the need for snail control to complement current interventions and accelerate schistosomiasis transmission interruption.http://www.sciencedirect.com/science/article/pii/S2405673125000030Malacological surveyBiomphalaria pfeifferiBiomphalaria camerunensisBulinus forskaliiSchistosoma mansoniNdikinimeki Health District |
| spellingShingle | Hervé Kengne Fogang Hugues C. Nana Djeunga Alvine C. Kengne-Fokam Murielle C. Tchami Mbagnia Flobert Njiokou Dickson S. Nsagha Emmanuel Yenshu Joseph Kamgno Residual transmission of schistosomiasis in Ndikinimeki Health District (Centre Region, Cameroon) despite implementation of complementary control strategies: Prospects for elimination Parasite Epidemiology and Control Malacological survey Biomphalaria pfeifferi Biomphalaria camerunensis Bulinus forskalii Schistosoma mansoni Ndikinimeki Health District |
| title | Residual transmission of schistosomiasis in Ndikinimeki Health District (Centre Region, Cameroon) despite implementation of complementary control strategies: Prospects for elimination |
| title_full | Residual transmission of schistosomiasis in Ndikinimeki Health District (Centre Region, Cameroon) despite implementation of complementary control strategies: Prospects for elimination |
| title_fullStr | Residual transmission of schistosomiasis in Ndikinimeki Health District (Centre Region, Cameroon) despite implementation of complementary control strategies: Prospects for elimination |
| title_full_unstemmed | Residual transmission of schistosomiasis in Ndikinimeki Health District (Centre Region, Cameroon) despite implementation of complementary control strategies: Prospects for elimination |
| title_short | Residual transmission of schistosomiasis in Ndikinimeki Health District (Centre Region, Cameroon) despite implementation of complementary control strategies: Prospects for elimination |
| title_sort | residual transmission of schistosomiasis in ndikinimeki health district centre region cameroon despite implementation of complementary control strategies prospects for elimination |
| topic | Malacological survey Biomphalaria pfeifferi Biomphalaria camerunensis Bulinus forskalii Schistosoma mansoni Ndikinimeki Health District |
| url | http://www.sciencedirect.com/science/article/pii/S2405673125000030 |
| work_keys_str_mv | AT hervekengnefogang residualtransmissionofschistosomiasisinndikinimekihealthdistrictcentreregioncameroondespiteimplementationofcomplementarycontrolstrategiesprospectsforelimination AT huguescnanadjeunga residualtransmissionofschistosomiasisinndikinimekihealthdistrictcentreregioncameroondespiteimplementationofcomplementarycontrolstrategiesprospectsforelimination AT alvineckengnefokam residualtransmissionofschistosomiasisinndikinimekihealthdistrictcentreregioncameroondespiteimplementationofcomplementarycontrolstrategiesprospectsforelimination AT muriellectchamimbagnia residualtransmissionofschistosomiasisinndikinimekihealthdistrictcentreregioncameroondespiteimplementationofcomplementarycontrolstrategiesprospectsforelimination AT flobertnjiokou residualtransmissionofschistosomiasisinndikinimekihealthdistrictcentreregioncameroondespiteimplementationofcomplementarycontrolstrategiesprospectsforelimination AT dicksonsnsagha residualtransmissionofschistosomiasisinndikinimekihealthdistrictcentreregioncameroondespiteimplementationofcomplementarycontrolstrategiesprospectsforelimination AT emmanuelyenshu residualtransmissionofschistosomiasisinndikinimekihealthdistrictcentreregioncameroondespiteimplementationofcomplementarycontrolstrategiesprospectsforelimination AT josephkamgno residualtransmissionofschistosomiasisinndikinimekihealthdistrictcentreregioncameroondespiteimplementationofcomplementarycontrolstrategiesprospectsforelimination |