A second photoactivatable state of the anion-conducting channelrhodopsin GtACR1 empowers persistent activity
Abstract Optogenetics is a method to regulate cells, tissues and organisms using light. It is applied to study neurons and to develop diagnostic and therapeutic tools for neuron-related diseases. The cation-conducting channelrhodopsin ChR2 triggers photoinduced depolarization of neuronal cells but g...
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| Main Authors: | Kristin Labudda, Mohamad Javad Norahan, Lisa-Marie Hübner, Philipp Althoff, Klaus Gerwert, Mathias Lübben, Till Rudack, Carsten Kötting |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-025-08560-4 |
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