MIR194-2HG, a miRNA host gene activated by HNF4A, inhibits gastric cancer by regulating microRNA biogenesis

Abstract Background MicroRNA host gene (MIRHG) lncRNA is a particular lncRNA subclass that can perform both typical and atypical lncRNA functions. The biological function of MIRHG lncRNA MIR194-2HG in cancer is poorly understood. Methods Loss-of-function studies were performed in vivo and in vitro t...

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Bibliographic Details
Main Authors: Hong Cao, Zidi Wang, Qiwei Guo, Shanshan Qin, Dandan Li
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Biology Direct
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Online Access:https://doi.org/10.1186/s13062-024-00549-z
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