Microwave-Assisted Method for Simultaneous Hydrolysis and Extraction for Preparation of Geniposidic Acid from Eucommia ulmoides Bark Using Basic Imidazolide Ionic Liquid
In order to hydrolyze geniposide and extract geniposidic acid, a novel microwave irradiation heating method for simultaneous hydrolysis and extraction for preparation of geniposidic acid from Eucommia ulmoides bark using basic imidazolide ionic liquid was developed in this work. Basic ionic liquid p...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | International Journal of Chemical Engineering |
| Online Access: | http://dx.doi.org/10.1155/2016/2135350 |
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| author | Lili Li Yupin Guo Chunchao Zhao Mengxia Wei Junling Liu Yuangang Zu Fei Wang Lei Yang |
| author_facet | Lili Li Yupin Guo Chunchao Zhao Mengxia Wei Junling Liu Yuangang Zu Fei Wang Lei Yang |
| author_sort | Lili Li |
| collection | DOAJ |
| description | In order to hydrolyze geniposide and extract geniposidic acid, a novel microwave irradiation heating method for simultaneous hydrolysis and extraction for preparation of geniposidic acid from Eucommia ulmoides bark using basic imidazolide ionic liquid was developed in this work. Basic ionic liquid paired by imidazolide anion and 1-hexyl-3-methylimidazolium cation ([C6mim]Im) was used as a dual hydrolysis catalyst and extraction solvent in the proposed approach. The optimal concentration of [C6mim]Im was 0.4 mol/L. And the independent parameters optimized by Box-Behnken design (BBD) based on single-factor tests were as follows: microwave irradiation time of 20 min at power of 415 W and liquid-solid ratio of 15 mL/g. Yield of geniposidic acid was increased to 3.41±0.17 μmol/g. DM130 macroporous resin, after reaction, was selected to separate geniposidic acid from hydrolysate. The plant materials with different treatment were analyzed by scanning electron microscopy (SEM) and thermogravimetric analysis (TG). The analysis of SEM and TG further indicated that IMSHE is an efficient preparation method for geniposidic acid. It is reasonable to assume that the method and the dual hydrolysis catalyst and extraction solvent would offer an alternative for the preparation of some other kinds of bioactive substances from plant materials. |
| format | Article |
| id | doaj-art-aa82413f21c743ef97b506ba274f7a52 |
| institution | Kabale University |
| issn | 1687-806X 1687-8078 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Chemical Engineering |
| spelling | doaj-art-aa82413f21c743ef97b506ba274f7a522025-02-03T06:47:25ZengWileyInternational Journal of Chemical Engineering1687-806X1687-80782016-01-01201610.1155/2016/21353502135350Microwave-Assisted Method for Simultaneous Hydrolysis and Extraction for Preparation of Geniposidic Acid from Eucommia ulmoides Bark Using Basic Imidazolide Ionic LiquidLili Li0Yupin Guo1Chunchao Zhao2Mengxia Wei3Junling Liu4Yuangang Zu5Fei Wang6Lei Yang7Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin 150040, ChinaCollege of Animal Science and Technology, Hebei North University, Zhangjiakou 075000, ChinaKey Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin 150040, ChinaKey Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin 150040, ChinaKey Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin 150040, ChinaKey Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin 150040, ChinaLandscape Architecture College, Northeast Forestry University, Harbin 150040, ChinaKey Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin 150040, ChinaIn order to hydrolyze geniposide and extract geniposidic acid, a novel microwave irradiation heating method for simultaneous hydrolysis and extraction for preparation of geniposidic acid from Eucommia ulmoides bark using basic imidazolide ionic liquid was developed in this work. Basic ionic liquid paired by imidazolide anion and 1-hexyl-3-methylimidazolium cation ([C6mim]Im) was used as a dual hydrolysis catalyst and extraction solvent in the proposed approach. The optimal concentration of [C6mim]Im was 0.4 mol/L. And the independent parameters optimized by Box-Behnken design (BBD) based on single-factor tests were as follows: microwave irradiation time of 20 min at power of 415 W and liquid-solid ratio of 15 mL/g. Yield of geniposidic acid was increased to 3.41±0.17 μmol/g. DM130 macroporous resin, after reaction, was selected to separate geniposidic acid from hydrolysate. The plant materials with different treatment were analyzed by scanning electron microscopy (SEM) and thermogravimetric analysis (TG). The analysis of SEM and TG further indicated that IMSHE is an efficient preparation method for geniposidic acid. It is reasonable to assume that the method and the dual hydrolysis catalyst and extraction solvent would offer an alternative for the preparation of some other kinds of bioactive substances from plant materials.http://dx.doi.org/10.1155/2016/2135350 |
| spellingShingle | Lili Li Yupin Guo Chunchao Zhao Mengxia Wei Junling Liu Yuangang Zu Fei Wang Lei Yang Microwave-Assisted Method for Simultaneous Hydrolysis and Extraction for Preparation of Geniposidic Acid from Eucommia ulmoides Bark Using Basic Imidazolide Ionic Liquid International Journal of Chemical Engineering |
| title | Microwave-Assisted Method for Simultaneous Hydrolysis and Extraction for Preparation of Geniposidic Acid from Eucommia ulmoides Bark Using Basic Imidazolide Ionic Liquid |
| title_full | Microwave-Assisted Method for Simultaneous Hydrolysis and Extraction for Preparation of Geniposidic Acid from Eucommia ulmoides Bark Using Basic Imidazolide Ionic Liquid |
| title_fullStr | Microwave-Assisted Method for Simultaneous Hydrolysis and Extraction for Preparation of Geniposidic Acid from Eucommia ulmoides Bark Using Basic Imidazolide Ionic Liquid |
| title_full_unstemmed | Microwave-Assisted Method for Simultaneous Hydrolysis and Extraction for Preparation of Geniposidic Acid from Eucommia ulmoides Bark Using Basic Imidazolide Ionic Liquid |
| title_short | Microwave-Assisted Method for Simultaneous Hydrolysis and Extraction for Preparation of Geniposidic Acid from Eucommia ulmoides Bark Using Basic Imidazolide Ionic Liquid |
| title_sort | microwave assisted method for simultaneous hydrolysis and extraction for preparation of geniposidic acid from eucommia ulmoides bark using basic imidazolide ionic liquid |
| url | http://dx.doi.org/10.1155/2016/2135350 |
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