Metformin-induced mitophagy suppresses auditory hair cell apoptosis via AMPK pathway

Metformin-induced mitophagy suppresses auditory hair cell apoptosis via AMPK pathway

Hearing loss is a pervasive issue affecting numerous individuals, and its etiology and categorization are multifaceted. Among these, sensorineural hearing loss (SNHL) emerges as the most prevalent variant among these. The primary causative factor underlying SNHL resides in the depletion of auditory...

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Bibliographic Details
Main Authors: Yifan Lai, Jiawei Qiu, Kuang Zheng, Xiang Li, Yinuo Lin, Zhengzheng Li, Haiqiu Sun
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Brain Research Bulletin
Subjects:
Metformin
Hearing loss
Autophagy
Mitophagy
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923025000267
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