The Diagnostic Challenge of an Infrequent Spectrum of Cryptococcus Infection
Cryptococcal infection results from inhalation of fungal spores and usually is confined to the lungs, but may disseminate systemically. Radiologically, cryptococcal infection has multiple forms of presentation. The diagnosis is usually based on fungal isolation from cultured clinical specimens. Long...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Radiology |
| Online Access: | http://dx.doi.org/10.1155/2019/5970648 |
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| author | Francisco Barbosa De Araujo Neto Camila Corona De Godoy Bueno Liege Tambelini Gomes Daniela Alejandra Ortiz Navas Mark Wanderley Stefanie Gallotti Borges Carneiro Rita Karine Veras Gomes De Mello Laura Mendes Coura Larissa Sayuri Missumi Henrique Durante Ricardo Francisco Cintra Zagatti Márcio Valente Yamada Sawamura |
| author_facet | Francisco Barbosa De Araujo Neto Camila Corona De Godoy Bueno Liege Tambelini Gomes Daniela Alejandra Ortiz Navas Mark Wanderley Stefanie Gallotti Borges Carneiro Rita Karine Veras Gomes De Mello Laura Mendes Coura Larissa Sayuri Missumi Henrique Durante Ricardo Francisco Cintra Zagatti Márcio Valente Yamada Sawamura |
| author_sort | Francisco Barbosa De Araujo Neto |
| collection | DOAJ |
| description | Cryptococcal infection results from inhalation of fungal spores and usually is confined to the lungs, but may disseminate systemically. Radiologically, cryptococcal infection has multiple forms of presentation. The diagnosis is usually based on fungal isolation from cultured clinical specimens. Long term antifungal therapy is recommended, but surgical procedures may eventually be necessary when large thoracic symptomatic masses are present. We report a case of a 41-year-old male, immunocompetent, investigating a palpable mass in the left supraclavicular region associated with unintentional weight loss over the last three months. He also reported chest pain in this period. Chest X-ray, ultrasonography, and computed tomography were performed, which diagnosed a mediastinal and left supraclavicular mass, interpreted as lymph node conglomerates of unknown etiology. He also underwent a biopsy of the left supraclavicular mass for etiological determination by histopathology, which confirmed cryptococcosis infection. Although very infrequent, mediastinal cryptococcal infection (simulating masses) is a challenging but important differential diagnosis of benign and malignant lesions, since its treatment is usually clinical. |
| format | Article |
| id | doaj-art-aa54ee6d64054c7391a806e77bef4b79 |
| institution | Kabale University |
| issn | 2090-6862 2090-6870 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Radiology |
| spelling | doaj-art-aa54ee6d64054c7391a806e77bef4b792025-02-03T07:26:11ZengWileyCase Reports in Radiology2090-68622090-68702019-01-01201910.1155/2019/59706485970648The Diagnostic Challenge of an Infrequent Spectrum of Cryptococcus InfectionFrancisco Barbosa De Araujo Neto0Camila Corona De Godoy Bueno1Liege Tambelini Gomes2Daniela Alejandra Ortiz Navas3Mark Wanderley4Stefanie Gallotti Borges Carneiro5Rita Karine Veras Gomes De Mello6Laura Mendes Coura7Larissa Sayuri Missumi8Henrique Durante9Ricardo Francisco Cintra Zagatti10Márcio Valente Yamada Sawamura11MD, Radiologist, Department of Radiology of the Medical School of the University of São Paulo, São Paulo, SP, BrazilMD, Doctor Resident in Radiology, Department of Radiology of the Medical School of the University of São Paulo, São Paulo, SP, BrazilMD, Doctor Resident in Radiology, Department of Radiology of the Medical School of the University of São Paulo, São Paulo, SP, BrazilMD, Pathology Resident, Department of Pathology of the Medical School of the University of São Paulo, São Paulo, SP, BrazilMD, Radiologist, Department of Radiology of the Medical School of the University of São Paulo, São Paulo, SP, BrazilMD, Radiologist, Department of Radiology of the Hospital Heliópolis, São Paulo, SP, BrazilMD, Radiologist, Department of Radiology of the Hospital Heliópolis, São Paulo, SP, BrazilMD, Doctor Resident in Radiology, Department of Radiology of the Medical School of the University of São Paulo, São Paulo, SP, BrazilMD, Doctor Resident in Radiology, Department of Radiology of the Medical School of the University of São Paulo, São Paulo, SP, BrazilMD, Doctor Resident in Radiology, Department of Radiology of the Medical School of the University of São Paulo, São Paulo, SP, BrazilMD, Radiologist, Department of Radiology of the Medical School of the University of São Paulo, São Paulo, SP, BrazilMD, Radiologist, Department of Radiology of the Medical School of the University of São Paulo, São Paulo, SP, BrazilCryptococcal infection results from inhalation of fungal spores and usually is confined to the lungs, but may disseminate systemically. Radiologically, cryptococcal infection has multiple forms of presentation. The diagnosis is usually based on fungal isolation from cultured clinical specimens. Long term antifungal therapy is recommended, but surgical procedures may eventually be necessary when large thoracic symptomatic masses are present. We report a case of a 41-year-old male, immunocompetent, investigating a palpable mass in the left supraclavicular region associated with unintentional weight loss over the last three months. He also reported chest pain in this period. Chest X-ray, ultrasonography, and computed tomography were performed, which diagnosed a mediastinal and left supraclavicular mass, interpreted as lymph node conglomerates of unknown etiology. He also underwent a biopsy of the left supraclavicular mass for etiological determination by histopathology, which confirmed cryptococcosis infection. Although very infrequent, mediastinal cryptococcal infection (simulating masses) is a challenging but important differential diagnosis of benign and malignant lesions, since its treatment is usually clinical.http://dx.doi.org/10.1155/2019/5970648 |
| spellingShingle | Francisco Barbosa De Araujo Neto Camila Corona De Godoy Bueno Liege Tambelini Gomes Daniela Alejandra Ortiz Navas Mark Wanderley Stefanie Gallotti Borges Carneiro Rita Karine Veras Gomes De Mello Laura Mendes Coura Larissa Sayuri Missumi Henrique Durante Ricardo Francisco Cintra Zagatti Márcio Valente Yamada Sawamura The Diagnostic Challenge of an Infrequent Spectrum of Cryptococcus Infection Case Reports in Radiology |
| title | The Diagnostic Challenge of an Infrequent Spectrum of Cryptococcus Infection |
| title_full | The Diagnostic Challenge of an Infrequent Spectrum of Cryptococcus Infection |
| title_fullStr | The Diagnostic Challenge of an Infrequent Spectrum of Cryptococcus Infection |
| title_full_unstemmed | The Diagnostic Challenge of an Infrequent Spectrum of Cryptococcus Infection |
| title_short | The Diagnostic Challenge of an Infrequent Spectrum of Cryptococcus Infection |
| title_sort | diagnostic challenge of an infrequent spectrum of cryptococcus infection |
| url | http://dx.doi.org/10.1155/2019/5970648 |
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